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Gene Expression Data
Assay Details
Assay
Reference: J:288446 Christians A, et al., Inflammation-like changes in the urothelium of Lifr-deficient mice and LIFR-haploinsufficient humans with urinary tract anomalies. Hum Mol Genet. 2020 May 8;29(7):1192-1204
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6472986
Gene symbol: Ezr
Gene name: ezrin
Antibody: anti-ezrin (3C12), (ab4069), (MS-661)
Detection system: Alexa Fluor 555
Results
Specimen S2 +/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: basal cell layer of ureter Present S2_EZRIN Lifr+/+ Expressed in the peripheral membrane.
TS26: intermediate cell layer of ureter Present S2_EZRIN Lifr+/+ Expressed in the peripheral membrane.
TS26: superficial cell layer of ureter Present S2_EZRIN Lifr+/+ Expressed in the peripheral membrane.
Specimen S2 -/-: embryonic day 18.5; Lifrtm1Imx/Lifrtm1Imx (more )
Structure Level Pattern Image Note
TS26: superficial cell layer of ureter Present S2_EZRIN Lifr-/- Expressed in the peripheral membrane, same as in the wild-type. Expression was dramatically downregulated in desquamated ureteric S-cells in the lumen.
TS26: basal cell layer of ureter Present S2_EZRIN Lifr-/- Expressed in the peripheral membrane, same as in the wild-type.
TS26: intermediate cell layer of ureter Present S2_EZRIN Lifr-/- Expressed in the peripheral membrane, same as in the wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory