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Gene Expression Data
Assay Details
Assay
Reference: J:173123 Mahoney Rogers AA, et al., Sprouty1 and Sprouty2 limit both the size of the otic placode and hindbrain Wnt8a by antagonizing FGF signaling. Dev Biol. 2011 May 1;353(1):94-104
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6471933
Gene symbol: Cdh1
Gene name: cadherin 1
Antibody: anti-E-cadherin
Detection system: Alexa Fluor 488
Results
Specimen 2F: embryonic day 9.0; Spry1tm1.1Jdli/Spry1+, Spry2tm1.1Mrt/Spry2+ (more )
Note: 19 somite stage
Structure Level Pattern Image Note
TS14: otic placode Present 2F Otic cup forms pointed ventral rim raised above surface ectoderm.
TS14: head surface ectoderm Present 2F

Specimen 2G: embryonic day 9.0; Spry1tm1.1Jdli/Spry1tm1.1Jdli, Spry2tm1.1Mrt/Spry2tm1.1Mrt (more )
Note: 19 somite stage
Structure Level Pattern Image Note
TS14: otic placode Present 2G Ventral rim of otic cup less distinct compared to controls.
TS14: head surface ectoderm Present 2G

Specimen 2H: embryonic day 9.5; Spry1tm1.1Jdli/Spry1+, Spry2tm1.1Mrt/Spry2+ (more )
Note: 23 somite stage
Structure Level Pattern Image Note
TS15: otic pit Present 2H Nearly completed closure to form otic vesicle.
TS15: head surface ectoderm Present 2H

Specimen 2I: embryonic day 9.5; Spry1tm1.1Jdli/Spry1tm1.1Jdli, Spry2tm1.1Mrt/Spry2tm1.1Mrt (more )
Note: 23 somite stage
Structure Level Pattern Image Note
TS15: otic pit Present 2I Otic cup fully open.
TS15: head surface ectoderm Present 2I


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory