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Tkfcem1Bcgen
Endonuclease-mediated Allele Detail
Summary
Symbol: Tkfcem1Bcgen
Name: triokinase, FMN cyclase; endonuclease-mediated mutation 1, Biocytogen LLC
MGI ID: MGI:6471029
Synonyms: Tk-
Gene: Tkfc  Location: Chr19:10565155-10583018 bp, - strand  Genetic Position: Chr19, 6.6 cM
Alliance: Tkfcem1Bcgen page
Mutation
origin
Strain of Origin:  Not Applicable
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
    Exons 2-9 were targeted with sgRNAs using CRISPR/Cas9 technology, resulting in a ~5 kb deletion. (J:296618)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tkfc Mutation:  40 strains or lines available
References
Original:  J:296618 Liu L, et al., Triose Kinase Controls the Lipogenic Potential of Fructose and Dietary Tolerance. Cell Metab. 2020 Oct 6;32(4):605-618.e7
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory