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Pcgf1tm1.1Hko
Targeted Allele Detail
Summary
Symbol: Pcgf1tm1.1Hko
Name: polycomb group ring finger 1; targeted mutation 1.1, Haruhiko Koseki
MGI ID: MGI:6470899
Synonyms: Pcgf1fl
Gene: Pcgf1  Location: Chr6:83054850-83057836 bp, + strand  Genetic Position: Chr6, 35.94 cM
Alliance: Pcgf1tm1.1Hko page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:243420
Parent Cell Line:  M1/M-1 (ES Cell)
Strain of Origin:  (129 x C57BL/6)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExons 2 through 7 were floxed. Flp-mediated recombination removed the selection cassette inserted downstream of exon 7. (J:243420)
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pcgf1 Mutation:  20 strains or lines available
References
Original:  J:243420 Almeida M, et al., PCGF3/5-PRC1 initiates Polycomb recruitment in X chromosome inactivation. Science. 2017 Jun 09;356(6342):1081-1084
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory