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Gene Expression Data
Assay Details
Assay
Reference: J:254460 Gou-Fabregas M, et al., 7-dehydrocholesterol efficiently supports Ret signaling in a mouse model of Smith-Opitz-Lemli syndrome. Sci Rep. 2016 Jun 23;6:28534
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6470858
Gene symbol: Ret
Gene name: ret proto-oncogene
Reporter: GFP
Direct Detection
Results
Specimen 2 E13.5 Dchr7+/+; Ret+/EGFP: embryonic day 13.5; Rettm13Jmi/Ret+, Tg(Pgk1-cre)1Lni/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: metanephros Present Regionally restricted 2_E13.5 Dhcr7+/+

Specimen 2 E13.5 Dhcr7-/-; Ret+/EGFP: embryonic day 13.5; Dhcr7tm1Gst/Dhcr7tm1Gst, Rettm13Jmi/Ret+, Tg(Pgk1-cre)1Lni/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: metanephros Present Regionally restricted 2_E13.5 Dhcr7-/- Authors report no overt difference in ureteric bud branching.

Specimen 2 E18.5 Dchr7+/+; Ret+/EGFP (upper): embryonic day 18.5; Rettm13Jmi/Ret+, Tg(Pgk1-cre)1Lni/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: metanephros Present Regionally restricted 2_E18.5 Dhcr7+/+ (upper)

Specimen 2 E18.5 Dhcr7-/-; Ret+/EGFP (upper): embryonic day 18.5; Dhcr7tm1Gst/Dhcr7tm1Gst, Rettm13Jmi/Ret+, Tg(Pgk1-cre)1Lni/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: metanephros Present Regionally restricted 2_E18.5 Dhcr7-/- (upper) Authors report no overt difference in ureteric bud branching.

Specimen 2 E18.5 Dchr7+/+; Ret+/EGFP (lower): embryonic day 18.5; Rettm13Jmi/Ret+, Tg(Pgk1-cre)1Lni/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: colon Present Regionally restricted 2_E18.5 Dhcr7+/+ (lower)
TS26: enteric ganglion Present Regionally restricted 2_E18.5 Dhcr7+/+ (lower)

Specimen 2 E18.5 Dhcr7-/-; Ret+/EGFP (lower): embryonic day 18.5; Dhcr7tm1Gst/Dhcr7tm1Gst, Rettm13Jmi/Ret+, Tg(Pgk1-cre)1Lni/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: colon Present Regionally restricted 2_E18.5 Dhcr7-/- (lower) Authors report no overt difference in plexus density.
TS26: enteric ganglion Present Regionally restricted 2_E18.5 Dhcr7-/- (lower) Authors report no overt difference in plexus density.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory