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Gene Expression Data
Assay Details
Assay
Reference: J:110696 Gonzalez MA, et al., Geminin is essential to prevent endoreduplication and to form pluripotent cells during mammalian development. Genes Dev. 2006 Jul 15;20(14):1880-4
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6470685
Gene symbol: Krt8
Gene name: keratin 8
Antibody: TROMA 1
Results
Specimen 2A: embryonic day 3.5 (more )
Note: Double labeled: blue - Troma-1 (Krt8); red - DAPI.
Structure Level Pattern Image Note
TS4: trophectoderm Present 2A Merge , 2A Troma-1
TS4: inner cell mass Absent 2A Troma-1 , 2A Merge
Specimen 2B 8-cell WT: embryonic day 2.5 (more )
Note: Triple labeled: blue - Troma-1 (Krt8); green - Geminin (Gmnn assay MGI:6470686); red - DAPI.
Structure Level Pattern Image Note
TS3: 8-cell stage conceptus Absent 2B 8-cell WT Merge , 2B 8-cell WT Troma-1 Total DNA
Specimen 2B 8-cell Mutant: embryonic day 3.5; GmnnGt(XT0615)Wtsi/GmnnGt(XT0615)Wtsi (more )
Note: Triple labeled: blue - Troma-1 (Krt8); green - Geminin (Gmnn assay MGI:6470686); red - DAPI.
Structure Level Pattern Image Note
TS3: 8-cell stage conceptus Present Regionally restricted 2B 8-cell Mutant Troma-1 Total DNA , 2B 8-cell Mutant Merge Expression in trophectoderm.
Specimen 2B 32-cell WT: embryonic day 3.5 (more )
Note: >32-cell stage. Triple labeled: blue - Troma-1 (Krt8); green - Geminin (Gmnn assay MGI:6470686); red - DAPI.
Structure Level Pattern Image Note
TS4: trophectoderm Present 2B 32-cell WT Troma-1 Total DNA , 2B 32-cell WT Merge
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory