Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Pdx1tm4.1(cre)Mgn
Name:	pancreatic and duodenal homeobox 1; targeted mutation 4.1, Mark A Magnuson
MGI ID:	MGI:6470616
Synonyms:	Pdx1creMgn
Gene:	Pdx1  Location: Chr5:147206907-147212658 bp, + strand  Genetic Position: Chr5, 86.84 cM
Alliance:	Pdx1tm4.1(cre)Mgn page

Germline Transmission:	Earliest citation of germline transmission: J:296396
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Pdx1tm4.1(cre)Mgn expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Pdx1 (MGI:102851)   Mutation details: RMCE on the loxed cassette acceptor (LCA) allele inserted an exon1 with an inframe cre recombinase. The hygromycin resistance cassette was removed in the final allele. (J:296396)

Activity:	Tissue activity of this recombinase allele
Driver:	Pdx1 (mouse) Summary of all recombinase alleles driven by Pdx1. Alliance mouse Pdx1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pdx1 Mutation:	35 strains or lines available

Original:	J:296396 Vanderbilt University, Labnodes. 2020;
All:	1 reference(s)