Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Sox17tm3.1(cre/ERT2)Mgn
Name:	SRY (sex determining region Y)-box 17; targeted mutation 3.1, Mark A Magnuson
MGI ID:	MGI:6470599
Synonyms:	Sox17tm1.2(cre/ERT2)Mgn
Gene:	Sox17  Location: Chr1:4561154-4567577 bp, - strand  Genetic Position: Chr1, 1.65 cM
Alliance:	Sox17tm3.1(cre/ERT2)Mgn page

Germline Transmission:	Earliest citation of germline transmission: J:296396
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Sox17tm3.1(cre/ERT2)Mgn expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Sox17 (MGI:107543)   Mutation details: Recombinase-mediated cassette exchange replaced the coding sequence with a cre/ERT2 fusing using the loxed cassette allele (LCA). Flp-mediated recombination removed the FRT-flanked hygromycin cassette. (J:296396)

Activity:	Tissue activity of this recombinase allele
Driver:	Sox17 (mouse) Summary of all recombinase alleles driven by Sox17. Alliance mouse Sox17 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sox17 Mutation:	28 strains or lines available

Original:	J:296396 Vanderbilt University, Labnodes. 2020;
All:	1 reference(s)