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Gene Expression Data
Assay Details
Assay
Reference: J:177133 Mehta V, et al., Atlas of Wnt and R-spondin gene expression in the developing male mouse lower urogenital tract. Dev Dyn. 2011 Nov;240(11):2548-60
Assay type: RNA in situ
MGI Accession ID: MGI:6470450
Gene symbol: Wnt2b
Gene name: wingless-type MMTV integration site family, member 2B
Probe: CVprobeWnt2b(0184)
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 4G: embryonic day 17.5 (more )
Note: Labeling was visualized using BM purple. The specimen was also stained for Cdh1 (red) to visualize the urothelium and Acta2 (green) to visualize the muscularis mucosa and muscularis propria.
Structure Level Pattern Image Note
TS25: lamina propria of dorsal pelvic urethra of female Strong 4G Expression is more abundant in the female versus male.
Specimen 4H: embryonic day 17.5 (more )
Note: Labeling was visualized using BM purple. The specimen was also stained for Cdh1 (red) to visualize the urothelium and Acta2 (green) to visualize the muscularis mucosa and muscularis propria.
Structure Level Pattern Image Note
TS25: intermediate cell layer of pelvic urethra of male Present 4H
TS25: superficial cell layer of pelvic urethra of male Present 4H
TS25: lamina propria of pelvic urethra of male Present 4H
TS25: lamina propria of seminal vesicle Present 4H Expression is present in the mesenchyme.
TS25: epithelium of seminal vesicle Present 4H
TS25: muscle layer of pelvic urethra of male Present Regionally restricted 4H Expression is present in a portion of the muscularis propria.
Specimen 4I: postnatal day 5 (more )
Note: Labeling was visualized using BM purple. The specimen was also stained for Cdh1 (red) to visualize the urothelium and Acta2 (green) to visualize the muscularis mucosa and muscularis propria.
Structure Level Pattern Image Note
TS28: submucosa of pelvic urethra of male Present 4I
TS28: peri-prostatic mesenchyme Present 4I
TS28: epithelium of pelvic urethra of male Absent 4I No expression in the urothelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory