Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Alb-Il22)8Bga
Name:	transgene insertion 8, Bin Gao
MGI ID:	MGI:6469893
Synonyms:	IL-22TG
Transgene:	Tg(Alb-Il22)8Bga  Location: unknown
Alliance:	Tg(Alb-Il22)8Bga page

Strain of Origin:

C57BL/6N

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Alb-Il22)8Bga expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Il22 (MGI:1355307)   Mutation details: The transgenic construct contains the murine IL-22 cDNA under the direction of a liver-specific albumin promoter. Four lines were found to express varying levels of IL-22, with line 8 expressing ~6000 pg/mL IL-22 in serum. (J:294662)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:294662 Park O, et al., In vivo consequences of liver-specific interleukin-22 expression in mice: Implications for human liver disease progression. Hepatology. 2011 Jul;54(1):252-61
All:	3 reference(s)