Gene Expression Data
Assay Details
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Assay
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Reference:
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J:287411
Tran HN, et al., Tcf7l2 transcription factor is required for the maintenance, but not the initial specification, of the neurotransmitter identity in the caudal thalamus. Dev Dyn. 2020 May;249(5):646-655
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6469623
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Gene symbol:
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Slc17a6
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Gene name:
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solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
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Probe:
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Slc17a6 probe
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
1A:
embryonic day 12.5
(more  )
Specimen
1A:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
1C:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tcf7l2tm1Cle/Tcf7l2tm1Cle
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: habenula |
Present |
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1C
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Similar as in the wild-type.
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| TS20: thalamus |
Present |
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1C
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Similar as in the wild-type. Expression was seen in the anterior region of the caudal thalamus.
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Specimen
1E:
embryonic day 12.5
(more )
Specimen
1E:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
1F:
embryonic day 12.5
(more )
Specimen
1F:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: thalamus |
Present |
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1F
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Expression was seen in the posterior thalamus.
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Specimen
1I:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tcf7l2tm1Cle/Tcf7l2tm1Cle
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: habenula |
Present |
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1I
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Similar as in the wild-type.
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| TS20: thalamus |
Present |
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1I
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Similar as in the wild-type. Expression was seen in the anterior region of the caudal thalamus.
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Specimen
1J:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tcf7l2tm1Cle/Tcf7l2tm1Cle
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: thalamus |
Present |
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1J
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Similar as in the wild-type. Expression was seen in the posterior region of the caudal thalamus.
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Specimen
3D:
embryonic day 16.5
(more )
Specimen
3D:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
3E:
embryonic day 16.5
(more )
Specimen
3E:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
3F:
embryonic day 16.5
(more )
Specimen
3F:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
3J:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tcf7l2tm1Cle/Tcf7l2tm1Cle
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: habenula |
Present |
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3J
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Similar as in the wild-type.
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| TS24: thalamic nucleus |
Present |
Regionally restricted |
3J
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Expression was specifically lost in the marginal region of caudal thalamus derivatives.
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Specimen
3K:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tcf7l2tm1Cle/Tcf7l2tm1Cle
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: habenula |
Present |
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3K
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Similar as in the wild-type.
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| TS24: thalamic nucleus |
Present |
Regionally restricted |
3K
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Expression was specifically lost in the marginal region of caudal thalamus derivatives.
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Specimen
3L:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Tcf7l2tm1Cle/Tcf7l2tm1Cle
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: habenula |
Present |
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3L
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Similar as in the wild-type.
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| TS24: thalamic nucleus |
Present |
Regionally restricted |
3L
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Expression was specifically lost in the marginal region of caudal thalamus derivatives.
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Analysis Tools