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Gene Expression Data
Assay Details
Assay
Reference: J:252161 Li N, et al., Mutations in the Histone Modifier PRDM6 Are Associated with Isolated Nonsyndromic Patent Ductus Arteriosus. Am J Hum Genet. 2016 Jun 2;98(6):1082-1091
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6469613
Gene symbol: Prdm6
Gene name: PR domain containing 6
Results
Specimen 6B E14.5 left: embryonic day 14.5 (more )
Note: Double labeled: green - Prdm6; red - Acta2 (assay MGI:6469614).
Structure Level Pattern Image Note
TS22: ductus arteriosus Present Regionally restricted 6B E14.5 PRDM6 left , 6B E14.5 Merge left Expression is in in smooth muscle cells and is absent in endothelial cells.
TS22: artery endothelium Absent 6B E14.5 PRDM6 left , 6B E14.5 Merge left

Specimen 6B E17.5 left: embryonic day 17.5 (more )
Note: Double labeled: green - Prdm6; red - Acta2 (assay MGI:6469614).
Structure Level Pattern Image Note
TS25: ductus arteriosus Present Regionally restricted 6B E17.5 Merge left , 6B E17.5 PRDM6 left Expression is in in smooth muscle cells and is absent in endothelial cells.
TS25: artery endothelium Absent 6B E17.5 Merge left , 6B E17.5 PRDM6 left

Specimen 6B P0.5 left: postnatal day 0.5 (more )
Note: Double labeled: green - Prdm6; red - Acta2 (assay MGI:6469614).
Structure Level Pattern Image Note
TS27: ductus arteriosus Weak 6B P0.5 Merge left , 6B P0.5 PRDM6 left
TS27: artery endothelium Absent 6B P0.5 Merge left , 6B P0.5 PRDM6 left

Specimen 6B E14.5 right: embryonic day 14.5 (more )
Note: Double labeled: green - Prdm6; red - Pecam1 (assay MGI:6469616).
Structure Level Pattern Image Note
TS22: ductus arteriosus Present Regionally restricted 6B E14.5 Merge right , 6B E14.5 PRDM6 right Expression is in in smooth muscle cells and is absent in endothelial cells.
TS22: artery endothelium Absent 6B E14.5 PRDM6 right , 6B E14.5 Merge right

Specimen 6B E17.5 right: embryonic day 17.5 (more )
Note: Double labeled: green - Prdm6; red - Pecam1 (assay MGI:6469616).
Structure Level Pattern Image Note
TS25: ductus arteriosus Present Regionally restricted 6B E17.5 Merge right , 6B E17.5 PRDM6 right Expression is in in smooth muscle cells and is absent in endothelial cells.
TS25: artery endothelium Absent 6B E17.5 Merge right , 6B E17.5 PRDM6 right

Specimen 6B P0.5 right: postnatal day 0.5 (more )
Note: Double labeled: green - Prdm6; red - Pecam1 (assay MGI:6469616).
Structure Level Pattern Image Note
TS27: ductus arteriosus Weak 6B P0.5 PRDM6 right , 6B P0.5 Merge right
TS27: artery endothelium Absent 6B P0.5 Merge right , 6B P0.5 PRDM6 right

Specimen 6C E14.5 left: embryonic day 14.5 (more )
Note: Double labeled: green - Prdm6; red - Acta2 (assay MGI:6469614).
Structure Level Pattern Image Note
TS22: artery smooth muscle Present Regionally restricted 6C E14.5 Merge left , 6C E14.5 PRDM6 left Expression is in the smooth muscle cells of the aorta.
TS22: dorsal aorta Present Regionally restricted 6C E14.5 Merge left , 6C E14.5 PRDM6 left Expression is in the smooth muscle cells of the aorta.
TS22: artery endothelium Absent 6C E14.5 PRDM6 left , 6C E14.5 Merge left

Specimen 6C E17.5 left: embryonic day 17.5 (more )
Note: Double labeled: green - Prdm6; red - Acta2 (assay MGI:6469614).
Structure Level Pattern Image Note
TS25: aorta Present Regionally restricted 6C E17.5 Merge left , 6C E17.5 PRDM6 left Expression is in the smooth muscle cells of the aorta.
TS25: artery smooth muscle Present Regionally restricted 6C E17.5 Merge left , 6C E17.5 PRDM6 left Expression is in the smooth muscle cells of the aorta.
TS25: artery endothelium Absent 6C E17.5 Merge left , 6C E17.5 PRDM6 left

Specimen 6C P0.5 left: postnatal day 0.5 (more )
Note: Double labeled: green - Prdm6; red - Acta2 (assay MGI:6469614).
Structure Level Pattern Image Note
TS27: aorta Present Regionally restricted 6C P0.5 PRDM6 left , 6C P0.5 Merge left Expression is in the smooth muscle cells of the aorta.
TS27: artery smooth muscle Present Regionally restricted 6C P0.5 PRDM6 left , 6C P0.5 Merge left Expression is in the smooth muscle cells of the aorta.
TS27: artery endothelium Absent 6C P0.5 Merge left , 6C P0.5 PRDM6 left

Specimen 6C E14.5 right: embryonic day 14.5 (more )
Note: Double labeled: green - Prdm6; red - Pecam1 (assay MGI:6469616).
Structure Level Pattern Image Note
TS22: artery smooth muscle Present Regionally restricted 6C E14.5 PRDM6 right , 6C E14.5 Merge right Expression is in the smooth muscle cells of the aorta.
TS22: dorsal aorta Present Regionally restricted 6C E14.5 PRDM6 right , 6C E14.5 Merge right Expression is in the smooth muscle cells of the aorta.
TS22: artery endothelium Absent 6C E14.5 PRDM6 right , 6C E14.5 Merge right

Specimen 6C E17.5 right: embryonic day 17.5 (more )
Note: Double labeled: green - Prdm6; red - Pecam1 (assay MGI:6469616).
Structure Level Pattern Image Note
TS25: aorta Present Regionally restricted 6C E17.5 Merge right , 6C E17.5 PRDM6 right Expression is in the smooth muscle cells of the aorta.
TS25: artery smooth muscle Present Regionally restricted 6C E17.5 Merge right , 6C E17.5 PRDM6 right Expression is in the smooth muscle cells of the aorta.
TS25: artery endothelium Absent 6C E17.5 Merge right , 6C E17.5 PRDM6 right

Specimen 6C P0.5 right: postnatal day 0.5 (more )
Note: Double labeled: green - Prdm6; red - Pecam1 (assay MGI:6469616).
Structure Level Pattern Image Note
TS27: aorta Present Regionally restricted 6C P0.5 PRDM6 right , 6C P0.5 Merge right Expression is in the smooth muscle cells of the aorta.
TS27: artery smooth muscle Present Regionally restricted 6C P0.5 PRDM6 right , 6C P0.5 Merge right Expression is in the smooth muscle cells of the aorta.
TS27: artery endothelium Absent 6C P0.5 PRDM6 right , 6C P0.5 Merge right


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory