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Gene Expression Data
Assay Details
Assay
Reference: J:262122 Gigante ED, et al., Hypomorphic Smo mutant with inefficient ciliary enrichment disrupts the highest level of vertebrate Hedgehog response. Dev Biol. 2018 May 15;437(2):152-162
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6469355
Gene symbol: Olig2
Gene name: oligodendrocyte transcription factor 2
Antibody: anti-Olig2 (AB9610)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 3G: embryonic day 10.5; Smocbb/Smo+ (more )
Note: Triple labeled: red - Olig2; green - Nkx2-2 (assay MGI:6469354); blue - Hoechst.
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 3G Expression in motor neuron precursons, dorsally adjacent to Nkx2.2-expressing cells.
Specimen 3H: embryonic day 10.5; Smocbb/Smocbb (more )
Note: Triple labeled: red - Olig2; green - Nkx2-2 (assay MGI:6469354); blue - Hoechst.
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 3H Expressing cells expanded ventrally, but not dorsally, compared to control.
Specimen 3K: embryonic day 11.5; Smocbb/Smo+ (more )
Note: Triple labeled: red - Olig2; green - Nkx2-2 (assay MGI:6469354); blue - Hoechst.
Structure Level Pattern Image Note
TS19: neural tube Present Regionally restricted 3K Expression domain adjacent to Nkx2.2 domain.
Specimen 3L: embryonic day 11.5; Smocbb/Smocbb (more )
Note: Triple labeled: red - Olig2; green - Nkx2-2 (assay MGI:6469354); blue - Hoechst.
Structure Level Pattern Image Note
TS19: neural tube Present Regionally restricted 3L Expression domain adjacent to Nkx2.2 domain.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory