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Gene Expression Data
Assay Details
Assay
Reference: J:242244 Ma X, et al., DAPL1, a susceptibility locus for age-related macular degeneration, acts as a novel suppressor of cell proliferation in the retinal pigment epithelium. Hum Mol Genet. 2017 May 01;26(9):1612-1621
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6469288
Gene symbol: Otx2
Gene name: orthodenticle homeobox 2
Antibody: OTX2 antibody
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 4G WT: postnatal month 8 (more )
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Present 4G WT Expression is evenly in a single layer.

Specimen 4G Dapl1-/-: postnatal month 8; Dapl1em1Nju/Dapl1em1Nju (more )
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Present Regionally restricted 4G Dapl1-/- Expression is raised and in multiple layers in this mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory