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Gene Expression Data
Assay Details
Assay
Reference: J:242244 Ma X, et al., DAPL1, a susceptibility locus for age-related macular degeneration, acts as a novel suppressor of cell proliferation in the retinal pigment epithelium. Hum Mol Genet. 2017 May 01;26(9):1612-1621
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6469276
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: anti-Ki67
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 3E E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: retina epithelium Present 3E E10.5
Specimen 3E E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: pigmented retinal epithelium Present 3E E13.5
Specimen 3E P1: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: pigmented retinal epithelium Present 3E P1
Specimen 3E P60: postnatal day 60 (more )
Structure Level Pattern Image Note
TS28: pigmented retinal epithelium Weak 3E P60
Specimen 4D WT: embryonic day 11.5 (more )
Note: Double labeled: red - Mki67; green - Pmel (assay MGI:6469286).
Structure Level Pattern Image Note
TS19: pigmented retinal epithelium Present 4D WT merge , 4D WT Ki67
Specimen 4D Dabl1-/-: embryonic day 11.5; Dapl1em1Nju/Dapl1em1Nju (more )
Note: Double labeled: red - Mki67; green - Pmel (assay MGI:6469286).
Structure Level Pattern Image Note
TS19: pigmented retinal epithelium Present 4D Dapl1-/- merge , 4D Dapl1-/- Ki67 There is an increase in positive cells in this mutant compared to wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory