Dab2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:205046 Moore R, et al., Differential requirement for Dab2 in the development of embryonic and extra-embryonic tissues. BMC Dev Biol. 2013;13:39
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6468336
Gene symbol:	Dab2
Gene name:	disabled 2, mitogen-responsive phosphoprotein

Antibody:

anti-Dab2

Results

2A Dab2 upper ©

Specimen 2A control: embryonic day 4.5 (more

)
Note: The sample could be from the heterozygous.

Structure	Level	Pattern	Image	Note
TS6: primitive endoderm	Present		2A Dab2 upper

2A Dab2 lower ©

Specimen 2A -/-: embryonic day 4.5; Dab2^tm2.2Xxx/Dab2^tm2.2Xxx (more

)

Structure	Level	Pattern	Image	Note
TS6: primitive endoderm	Absent		2A Dab2 lower

2B WT upper ©

Specimen 2B WT: embryonic day 5.5 (more

)

Structure	Level	Pattern	Image	Note
TS7: primitive endoderm	Present		2B WT upper

2B1 upper ©

Specimen 2B #1 -/-: embryonic day 5.5; Dab2^tm2.2Xxx/Dab2^tm2.2Xxx (more

)

Structure	Level	Pattern	Image	Note
TS7: primitive endoderm	Absent		2B1 upper

2B2 upper ©

Specimen 2B #2 -/-: embryonic day 5.5; Dab2^tm2.2Xxx/Dab2^tm2.2Xxx (more

)

Structure	Level	Pattern	Image	Note
TS7: primitive endoderm	Absent		2B2 upper

2B3 upper ©

Specimen 2B #3 -/-: embryonic day 5.5; Dab2^tm2.2Xxx/Dab2^tm2.2Xxx (more

)

Structure	Level	Pattern	Image	Note
TS7: primitive endoderm	Absent		2B3 upper

2B4 upper ©

Specimen 2B #4 -/-: embryonic day 5.5; Dab2^tm2.2Xxx/Dab2^tm2.2Xxx (more

)

Structure	Level	Pattern	Image	Note
TS7: primitive endoderm	Absent		2B4 upper

2B5 upper ©

Specimen 2B #5 -/-: embryonic day 5.5; Dab2^tm2.2Xxx/Dab2^tm2.2Xxx (more

)

Structure	Level	Pattern	Image	Note
TS7: primitive endoderm	Absent		2B5 upper

3B ©

Specimen 3B: postnatal month 3; Dab2^tm2.1Xxx/Dab2^tm2.2Xxx (more

)

Structure	Level	Pattern	Image	Note
TS28: renal proximal tubule	Present	Uniform	3B	Kidney proximal tubular epithelial cells were evenly positive.

3C ©

Specimen 3C: postnatal month 3; Dab2^tm2.1Xxx/Dab2^tm2.2Xxx, Meox2^tm1(cre)Sor/Meox2⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS28: renal proximal tubule	Present		3C	Expression was lost in 90% or more of the cells.

3F ©

Specimen 3F: postnatal adult; Dab2^tm2.1Xxx/Dab2⁺, Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS28: renal proximal tubule	Present	Uniform	3F	Kidney proximal tubular epithelial cells were evenly positive.

3G ©

Specimen 3G: postnatal adult; Dab2^tm2.1Xxx/Dab2^tm2.2Xxx, Edil3^{Tg(Sox2-cre)1Amc}/Edil3⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS28: renal proximal tubule	Absent		3G

3H ©

Specimen 3H: postnatal adult; Dab2^tm2.1Xxx/Dab2^tm2.2Xxx, Meox2^tm1(cre)Sor/Meox2⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS28: renal proximal tubule	Present		3H	Expression was lost in 90% or more of the cells.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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