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Gene Expression Data
Assay Details
Assay
Reference: J:270314 Mitomo K, et al., Sphenoid bone hypoplasia is a skeletal phenotype of cleidocranial dysplasia in a mouse model and patients. Bone. 2019 Mar;120:176-186
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6468212
Gene symbol: Sp7
Gene name: Sp7 transcription factor 7
Antibody: Anti-Sp7/Osterix antibody (ab22552)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 1G: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: sphenoid bone Present Scattered 1G Positive cells are scattered throughout the region of mesenchymal cell condensation in the medial pterygoid process region of sphenoid bone.

Specimen 1H: embryonic day 14.5; Runx2tm1Kish/Runx2+ (more )
Structure Level Pattern Image Note
TS22: sphenoid bone Present Single cells 1H There are a few scattered positive cells in the medial pterygoid process region of sphenoid bone.

Specimen 2G: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: sphenoid bone Present Scattered 2G Positive cells are scattered around the osteoid, and small flattened cells are located at the cranial region of mesenchymal-cell condensation.

Specimen 2H: embryonic day 15.5; Runx2tm1Kish/Runx2+ (more )
Structure Level Pattern Image Note
TS23: sphenoid bone Present Single cells 2H There are a few positive cells scattered at the cranial region of mesenchymal-cell condensation.

Specimen 3G: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: sphenoid bone Present Scattered 3G Positive cells are scattered around the trabecular bones and the cartilage at the lower part of the medial pterygoid process region.

Specimen 3H: embryonic day 16.5; Runx2tm1Kish/Runx2+ (more )
Structure Level Pattern Image Note
TS24: sphenoid bone Present Regionally restricted 3H Positive cells were seen beneath the cartilage and at the medial pterygoid process.

Specimen 4G: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: sphenoid bone Present Regionally restricted 4G Positive cells are scattered in two-thirds of the cranial side of the medial pterygoid process around the trabecular bones and beneath the cartilage in the lower part of the medial pterygoid process region.

Specimen 4H: embryonic day 18.5; Runx2tm1Kish/Runx2+ (more )
Structure Level Pattern Image Note
TS26: sphenoid bone Present 4H Positive cells are distributed at the central area in osteoid-like tissue and beneath the cartilage of the medial pterygoid process region.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/20/2026
MGI 6.24
The Jackson Laboratory