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Gene Expression Data
Assay Details
Assay
Reference: J:295480 Haage A, et al., Precise coordination of cell-ECM adhesion is essential for efficient melanoblast migration during development. Development. 2020 Jul 17;147(14):dev184234
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6467319
Gene symbol: Dct
Gene name: dopachrome tautomerase
Antibody: Dct antibody
Detection system: Alexa Fluor 488
Results
Specimen 1I Dorsal: postnatal week 4 (more )
Note: Double labeled: green - Dct; white - DAPI.
Structure Level Pattern Image Note
TS28: hair follicle Present Regionally restricted 1I Dorsal Authors report similar numbers of melanocytes per hair follicle in dorsal skin in wild-type and mutants.
Specimen 1J Dorsal: postnatal week 4; Tln1tm1.2Geno/Tln1tm1.2Geno (more )
Note: Double labeled: green - Dct; white - DAPI.
Structure Level Pattern Image Note
TS28: hair follicle Present Regionally restricted 1J Dorsal Authors report similar numbers of melanocytes per hair follicle in dorsal skin in wild-type and mutants.
Specimen 1I Ventral: postnatal week 4 (more )
Note: Double labeled: green - Dct; white - DAPI.
Structure Level Pattern Image Note
TS28: hair follicle Present Regionally restricted 1I Ventral
Specimen 1J Ventral: postnatal week 4; Tln1tm1.2Geno/Tln1tm1.2Geno (more )
Note: Double labeled: green - Dct; white - DAPI.
Structure Level Pattern Image Note
TS28: hair follicle Weak Regionally restricted 1J Ventral Decreased number of Dct-expressing melanocytes per hair follicle in ventral skin.
Specimen 1M: postnatal week 4 (more )
Structure Level Pattern Image Note
TS28: hair follicle Present Regionally restricted 1M inset , 1M
Specimen 1N: postnatal week 4; Tln1tm1.2Geno/Tln1tm1.2Geno (more )
Structure Level Pattern Image Note
TS28: hair follicle Weak Regionally restricted 1N , 1N inset
Specimen 3A: embryonic day 15.5 (more )
Note: Specimens collected 4 hours following injection of EdU. Triple labeled: green - Dct; red - EdU; blue - DAPI.
Structure Level Pattern Image Note
TS23: trunk skin Present 3A (upper) , 3A DCT Authors report similar numbers of Dct and EdU double-labeled cells in mutant and control embryos at both time points.
Specimen 3B: embryonic day 15.5; Tln1tm1.2Geno/Tln1tm1.2Geno (more )
Note: Specimens collected 4 hours following injection of EdU. Triple labeled: green - Dct; red - EdU; blue - DAPI.
Structure Level Pattern Image Note
TS23: trunk skin Present 3B (upper) , 3B DCT Authors report similar numbers of Dct and EdU double-labeled cells in mutant and control embryos at both time points.
Specimen 3C: embryonic day 15.5 (more )
Note: Specimens collected 24 hours following injection of EdU. Triple labeled: green - Dct; red - EdU; blue - DAPI.
Structure Level Pattern Image Note
TS23: trunk skin Present 3C (upper) , 3C DCT Authors report similar numbers of Dct and EdU double-labeled cells in mutant and control embryos at both time points.
Specimen 3D: embryonic day 15.5; Tln1tm1.2Geno/Tln1tm1.2Geno (more )
Note: Specimens collected 24 hours following injection of EdU. Triple labeled: green - Dct; red - EdU; blue - DAPI.
Structure Level Pattern Image Note
TS23: trunk skin Present 3D (upper) , 3D DCT
Specimen 3F +/+: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: trunk skin Present 3F +/+
Specimen 3F E1770A/E1770A: embryonic day 15.5; Tln1tm1.2Geno/Tln1tm1.2Geno (more )
Structure Level Pattern Image Note
TS23: trunk skin Present 3F E1170A/E1170A
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory