About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:162061 Slaten ER, et al., Transient expression of serotonin 5-HT4 receptors in the mouse developing thalamocortical projections. Dev Neurobiol. 2010 Feb 15;70(3):165-81
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6460412
Gene symbol: Htr4
Gene name: 5 hydroxytryptamine (serotonin) receptor 4
Antibody: SR-4 (C-18) antibody (sc-32566)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1A: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cortical plate Present Regionally restricted 1A Expression in anterior cortical plate.
TS25: corpus striatum Present 1A
TS25: hippocampus Present 1A

Specimen 3A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: diencephalon Present Regionally restricted 3A Expression in fibers in lateral diencephalon which appear to abruptly change direction between caudal and rostral diencephalon, and advance in the caudal-rostral direction in the rostral diencephalon.

Specimen 3C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: diencephalon Present Regionally restricted 3C Expression in lateral diencephalon.
TS21: corpus striatum Present Regionally restricted 3C Expression in a stream of fibers in the striatum.

Specimen 3D: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: diencephalon Present Regionally restricted 3D Expression in fibers in lateral diencephalon.

Specimen 4B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: diencephalon Strong Regionally restricted 4B Strong expression in fibers originating in diencephalon.
TS23: corpus striatum Strong Regionally restricted 4B Strong expression in fibers entering striatum.
TS23: brainstem Strong Regionally restricted 4B Strong expression in lower brainstem.

Specimen 4C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: diencephalon Strong Regionally restricted 4C Strong expression in fibers originating in diencephalon.
TS23: corpus striatum Strong Regionally restricted 4C Strong expression in fibers entering striatum.

Specimen 4D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: corpus striatum Present Regionally restricted 4D Expression in fascicles formed by fibers in striatum.

Specimen 4E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: diencephalon internal capsule Present Regionally restricted 4E Expression in fibers entering internal capsule.

Specimen 4F: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: diencephalon Strong Regionally restricted 4F Strong expression in fibers originating in diencephalon.

Specimen 5A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: neocortex Present Regionally restricted 5A Expression in fibers turning rostrally to reach the frontal cortex and providing dense input to the developing anterior cingulate cortex.

Specimen 5B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: corpus striatum Strong Regionally restricted 5B Strong expression in fibers in the striatum.

Specimen 5C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: forebrain Strong Regionally restricted 5C Strong expression in fibers at telencephalon-diencephalon junction.

Specimen 5D: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: neocortex Present Regionally restricted 5D Expression in fibers turning rostrally to reach the frontal cortex and providing dense input to the developing anterior cingulate cortex.

Specimen 5E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: corpus striatum Strong Regionally restricted 5E Strong expression in fibers in the striatum.

Specimen 5F: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: forebrain Strong Regionally restricted 5F Strong expression in fibers at telencephalon-diencephalon junction.

Specimen 7B: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: forebrain Weak Regionally restricted 7B Low expression in thalamocortical projections in diencephalon-telencephalon junction and striatum.
TS25: diencephalon internal capsule Absent 7B No expression in thalamocortical fibers entering internal capsule.

Specimen 7D: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: forebrain Weak Regionally restricted 7D Low expression in thalamocortical projections in diencephalon-telencephalon jusnction and striatum.
TS25: cerebral cortex intermediate zone Strong Regionally restricted 7D Strong expression in putative thalamocortical fibers in cortical intermediate zone.

Specimen 8A: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cortical plate Present 8A
TS25: cerebral cortex intermediate zone Present 8A

Specimen 8B: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cortical plate Present 8B
TS25: cerebral cortex intermediate zone Present Regionally restricted 8B Stronger expression in cortical layers immediately above expressing fibers.

Specimen 8C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebral cortex intermediate zone Present 8C

Specimen 8D: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebral cortex intermediate zone Strong Regionally restricted 8D Stronger expression in cortical layers immediately above expressing fibers.

Specimen 8F: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebral cortex intermediate zone Present 8F
TS25: cerebral cortex marginal zone Absent 8F No expression in fibers in marginal zone.

Specimen P3 not shown: postnatal day 3 (more )
Structure Level Pattern Image Note
TS27: brain Present Regionally restricted No expression in thalamocortical fibers postnatally.

Specimen 10B: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: brain Present Regionally restricted 10B No expression in thalamocortical fibers postnatally.
TS28: amygdala Strong 10B
TS28: hippocampus Strong 10B
TS28: hypothalamus Strong 10B
TS28: piriform cortex Strong 10B

Specimen 10C: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: habenula Strong 10C

Specimen 10D: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: hippocampus Strong 10D


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/18/2025
MGI 6.24
The Jackson Laboratory