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Gene Expression Data
Assay Details
Assay
Reference: J:41553 Jurata LW, et al., Nuclear LIM interactor, a rhombotin and LIM homeodomain interacting protein, is expressed early in neuronal development. Proc Natl Acad Sci U S A. 1996 15;93(21):11693-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6460076
Gene symbol: Ldb1
Gene name: LIM domain binding 1
Antibody: anti-NLI 4508
Detection system: fluorescein
Results
Specimen 18 somite stage not shown: embryonic day 9.0 (more )
Structure Level Pattern Image Note
TS14: future spinal cord Present Regionally restricted Expression in neurons located at peripheral most region of intermediate zone.
Specimen 4b/c: embryonic day 9.5 (more )
Note: Double labeled: red - NLI (Ldb1); green - Isl1 (assay MGI:6460075).
Structure Level Pattern Image Note
TS15: future spinal cord Present Regionally restricted 4c , 4b Expression predominantly in lateral most region of intermediate zone. Nuclear coexpression with Isl1 in all neural tube motor neurons at brachial level.
Specimen 4d: embryonic day 9.5 (more )
Note: Double labeled: red - NLI (Ldb1); green - NF-M (Nefm assay MGI:6460077).
Structure Level Pattern Image Note
TS15: future spinal cord Present Regionally restricted 4d Nuclear expression in neuronal cells expressing cytoplasmic NF-M (Nefm).
Specimen E9.5 not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future hindbrain Present Regionally restricted Co-expression with NF-M (Nefm) in ventral cells of hindbrain epithelium. No expression in dorsal cells types in this region until later stages.
Specimen 4f/g: embryonic day 10.5 (more )
Note: Double labeled: red - NLI (Ldb1); green - NF-M (Nefm assay MGI:6460077).
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 4f , 4g Expressing cells include commissural neurons, interneurons and motor neurons at brachial level.
TS17: dorsal root ganglion Present Regionally restricted 4f , 4g Expression in sensory neuron in dorsal root ganglion.
Specimen 4h: embryonic day 10.5 (more )
Note: Double labeled: red - NLI (Ldb1); green - NF-M (Nefm assay MGI:6460077).
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 4h Expression in medial neural tube not expressing NF-M (NEFM)
Specimen E10.5 not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: cranial ganglion Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/28/2024
MGI 6.13 		The Jackson Laboratory