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Gene Expression Data
Assay Details
Assay
Reference: J:292099 Aherrahrou R, et al., CYP17A1 deficient XY mice display susceptibility to atherosclerosis, altered lipidomic profile and atypical sex development. Sci Rep. 2020 May 29;10(1):8792
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6459990
Gene symbol: Cyp17a1
Gene name: cytochrome P450, family 17, subfamily a, polypeptide 1
Antibody: anti-Cyp17a1 (C-17; sc-46081)
Detection system: Secondary antibody
Results
Specimen S1a: embryonic day 16.0; Cyp17a1tm1a(EUCOMM)Wtsi/Cyp17a1+ (more )
Structure Cell Type Level Pattern Image Note
TS24: Leydig cell Leydig cell Present S1a
Specimen S1b: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: Leydig cell Leydig cell Present S1b
Specimen S1e: postnatal adult; Cyp17a1tm1a(EUCOMM)Wtsi/Cyp17a1+ (more )
Structure Level Pattern Image Note
TS28: epithelium of epididymis Present S1e
Specimen S2a: postnatal adult; Apoetm1Unc/Apoetm1Unc (more )
Structure Cell Type Level Pattern Image Note
TS28: Leydig cell Leydig cell Present S2a , S2a inset
Specimen S2b: postnatal adult; Apoetm1Unc/Apoetm1Unc, Cyp17a1tm1a(EUCOMM)Wtsi/Cyp17a1tm1a(EUCOMM)Wtsi (more )
Structure Cell Type Level Pattern Image Note
TS28: Leydig cell Leydig cell Absent S2b inset , S2b
Specimen S2c: postnatal year 1; Apoetm1Unc/Apoetm1Unc (more )
Structure Level Pattern Image Note
TS28: aorta Weak Single cells S2c inset , S2c Expression is seen in a few cells that have infiltrated the aortic plaque cap.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory