Tg(Cdx2-Tgfbr1*)#Mllo
Transgene Detail
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Symbol: |
Tg(Cdx2-Tgfbr1*)#Mllo |
Name: |
transgene insertion, Moises Mallo |
MGI ID: |
MGI:6458913 |
Synonyms: |
Cdx2P-Alk5CA |
Transgene: |
Tg(Cdx2-Tgfbr1*)#Mllo Location: unknown
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Alliance: |
Tg(Cdx2-Tgfbr1*)#Mllo page
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Strain of Origin: |
Not Applicable
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Cdx2-Tgfbr1*)#Mllo expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Tgfbr1 (MGI:98728) |
modified Tgfbr1 cDNA (threonine to aspartic acid, p.T200D) that codes for a constitutively active form |
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Mutation details: An enhancer element from the Cdx2 gene that drives expression in the posterior epiblast and the primitive streak drives the expression of a modified Tgfbr1 cDNA (threonine to aspartic acid, p.T200D) that codes for a constitutively active form.
(J:198634)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:198634 Jurberg AD, et al., Switching axial progenitors from producing trunk to tail tissues in vertebrate embryos. Dev Cell. 2013 Jun 10;25(5):451-62 |
All: |
2 reference(s) |
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