Pdx1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:155058 Zhang H, et al., Multiple, temporal-specific roles for HNF6 in pancreatic endocrine and ductal differentiation. Mech Dev. 2009 Dec;126(11-12):958-73
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6458836
Gene symbol:	Pdx1
Gene name:	pancreatic and duodenal homeobox 1

Antibody:

anti-Pdx1

Results

1Ba ©

Specimen 1Ba: embryonic day 11.5; Onecut1^tm1.1Mga/Onecut1^tm1.1Mga (more

)
Note: Double labeled: red - Pdx1; green - HNF6 (Onecut1 assay MGI:6458834).

Structure	Level	Pattern	Image	Note
TS19: pancreas primordium epithelium	Present		1Ba

1Bb ©

Specimen 1Bb: embryonic day 11.5; Onecut1^tm1.1Mga/Onecut1^tm1.1Mga, Tg(Pdx1-cre)89.1Dam/0 (more

)
Note: Conditional mutant. Double labeled: red - Pdx1; green - HNF6 (Onecut1 assay MGI:6458834).

Structure	Level	Pattern	Image	Note
TS19: pancreas primordium epithelium	Present		1Bb

3A ©

Specimen 3A: embryonic day 14.5; Onecut1^tm1.1Mga/Onecut1^tm1.1Mga (more

)
Note: Double labeled: red - Pdx1; green - Glu (Gcg assay MGI:6458837).

Structure	Level	Pattern	Image	Note
TS22: pancreas epithelium	Present		3A

3B ©

Specimen 3B: embryonic day 14.5; Onecut1^tm1.1Mga/Onecut1^tm1.1Mga, Tg(Pdx1-cre)89.1Dam/0 (more

)
Note: Conditional mutant. Double labeled: red - Pdx1; green - Glu (Gcg assay MGI:6458837).

Structure	Level	Pattern	Image	Note
TS22: pancreas epithelium	Present	Regionally restricted	3B	Less branching of epithelium compared with controls,

S2C ©

Specimen S2C: postnatal day 2; Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor⁺, Onecut1^tm1.1Mga/Onecut1^tm1.1Mga, Tg(Neurog3-cre)C1Able/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS27: pancreas	Present		S2C	Authors report localization of expression comparable to controls.

Specimen Adult not shown: postnatal adult; Onecut1^tm1.1Mga/Onecut1^tm1.1Mga, Tg(Pdx1-cre)89.1Dam/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS28: pancreas	Present	Regionally restricted		Expressing cells abnormally located within multilayered epithelium. Mutant pancreatic epithelium never fully filled the mesenchyme postnatally.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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