Gene Expression Data
Assay Details
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Assay
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Reference:
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J:241779
Hu J, et al., Opposing FlnA and FlnB interactions regulate RhoA activation in guiding dynamic actin stress fiber formation and cell spreading. Hum Mol Genet. 2017 Apr 01;26(7):1294-1304
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6457453
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Gene symbol:
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Flna
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Gene name:
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filamin, alpha
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Antibody:
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anti-FLNA (Cat. 2242)
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Detection system:
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Secondary antibody coupled to rhodamine
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Assay notes:
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Fixative was 10% trichloroacetic acid.
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Results
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Specimen
2D control:
postnatal newborn
(more  )
Specimen
2D control:
(close  )
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Genetic Background:
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Not Specified
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Age:
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postnatal newborn
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: radius |
Present |
Regionally restricted |
2D control top
,
2D control bottom
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Expression is in the growth plate.
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Specimen
2D FlnB-/-:
(close )
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Genetic Background:
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involves: 129S6/SvEvTac
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Mutant Allele(s):
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Flnbtm1Vshn/Flnbtm1Vshn
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Age:
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postnatal newborn
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: radius |
Present |
Regionally restricted |
2D FlnB-/- top
,
2D FlnB-/- bottom
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Expression in this mutant is decreased in the hypertrophic zone and increased in the proliferative zone of the growth plate.
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Analysis Tools
