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Gene Expression Data
Assay Details
Assay
Reference: J:150728 Zhao J, et al., HnRNP U mediates the long-range regulation of Shh expression during limb development. Hum Mol Genet. 2009 Aug 15;18(16):3090-7
Assay type: RNA in situ
MGI Accession ID: MGI:6457125
Gene symbol: Dkk1
Gene name: dickkopf WNT signaling pathway inhibitor 1
Probe: Dkk1 probe8
Probe preparation: Antisense RNA
Results
Specimen 1D WT F: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: forelimb mesenchyme Present Regionally restricted 1D WT Forelimb Expression is in a stripe in the anterior and posterior necrotic zones.
TS20: forelimb epithelium Present Regionally restricted 1D WT Forelimb Expression is in the apical ectodermal ridge.

Specimen 1D WT H: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: hindlimb mesenchyme Present Regionally restricted 1D WT Hindlimb Expression is in a stripe in the anterior and posterior necrotic zones.
TS20: hindlimb epithelium Present Regionally restricted 1D WT Hindlimb Expression is in the apical ectodermal ridge.

Specimen 1D DZm/m F: embryonic day 12.0; Rr29Dz/Rr29Dz (more )
Structure Level Pattern Image Note
TS20: forelimb mesenchyme Weak Regionally restricted 1D DZm/m Forelimb Expression is reduced in the posterior necrotic zone and is greatly reduced in the anterior necrotic zone in this mutant.
TS20: forelimb epithelium Weak Regionally restricted 1D DZm/m Forelimb Expression is in the apical ectodermal ridge.

Specimen 1D DZm/m H: embryonic day 12.0; Rr29Dz/Rr29Dz (more )
Structure Level Pattern Image Note
TS20: hindlimb mesenchyme Weak Regionally restricted 1D DZm/m Hindlimb Expression is reduced in the posterior necrotic zone and is greatly reduced in the anterior necrotic zone in this mutant.
TS20: hindlimb epithelium Weak Regionally restricted 1D DZm/m Hindlimb Expression is in the apical ectodermal ridge.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory