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Gene Expression Data
Assay Details
Assay
Reference: J:181134 Tang ZZ, et al., Muscle weakness in myotonic dystrophy associated with misregulated splicing and altered gating of CaV1.1 calcium channel. Hum Mol Genet. 2012 Mar 15;21(6):1312-24
Assay type: RT-PCR
MGI Accession ID: MGI:6456558
Gene symbol: Cacna1s
Gene name: calcium channel, voltage-dependent, L type, alpha 1S subunit
Probe: CaV1.1-E29-Fwd, CaV1.1-E29-Rev
Assay notes: Primers were 5' end labeled with 56-FAM.
Results Image: 4B CaV1.1-E29
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Amount Genetic BackgroundMutant Allele(s)Sex
WT P m 6 TS28: heart ventricle Present (b) Not Specified; poly-A+ RNA involves: 129S1/Sv Male
WT P m 6 TS28: heart ventricle Present (c) Not Specified; poly-A+ RNA involves: 129S1/Sv Male
Mbnl1+/deltaE3 P m 6 TS28: heart ventricle Present (d) Not Specified; poly-A+ RNA involves: 129S1/Sv Mbnl1tm1Sws/Mbnl1+Male
Mbnl1+/deltaE3 P m 6 TS28: heart ventricle Present (e) Not Specified; poly-A+ RNA involves: 129S1/Sv Mbnl1tm1Sws/Mbnl1+Male
Mbnl1deltaE3/deltaE3 P m 6 TS28: heart ventricle Present (f) Not Specified; poly-A+ RNA involves: 129S1/Sv Mbnl1tm1Sws/Mbnl1tm1SwsMale
Mbnl1deltaE3/deltaE3 P m 6 TS28: heart ventricle Present (g) Not Specified; poly-A+ RNA involves: 129S1/Sv Mbnl1tm1Sws/Mbnl1tm1SwsMale
Mbnl1deltaE3/deltaE3 P m 6 TS28: heart ventricle Present (h) Not Specified; poly-A+ RNA involves: 129S1/Sv Mbnl1tm1Sws/Mbnl1tm1SwsMale
Notes:
(a) There are two bands, a band that included exon 29 and a band that skipped exon 29.
(b) 76% of the muscle included exon 29.
(c) 78% of the muscle included exon 29.
(d) 75% of the muscle included exon 29.
(e) 74% of the muscle included exon 29.
(f) 20% of the muscle included exon 29.
(g) 19% of the muscle included exon 29.
(h) 21% of the muscle included exon 29.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory