Tg(Cd4-CD2)dDarl
Transgene Detail
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| Symbol: |
Tg(Cd4-CD2)dDarl |
| Name: |
transgene insertion d, Dan R Littman |
| MGI ID: |
MGI:6456190 |
| Transgene: |
Tg(Cd4-CD2)dDarl Location: unknown
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| Alliance: |
Tg(Cd4-CD2)dDarl page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Humanized sequence, Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Cd4-CD2)dDarl expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
CD2 (914) |
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mouse promoter, human cDNA |
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Tg(Cd4-CD2)dDarl expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Cd4 (MGI:88335) |
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Mutation details: A mouse Cd4 minigene consisting of the upstream enhancer, promoter (0.5 kb), 5' UTR-containing exon 1, start and end of intron 1 (internal deletion of PstI-SacI fragment) and the 5' UTR part of the start codon-containing exon 2, was linked to the human CD2 cDNA sequence, followed by SV40 poly(A) signal sequence.
(J:18902)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:18902 Sawada S, et al., A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development. Cell. 1994 Jun 17;77(6):917-29 |
| All: |
1 reference(s) |
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Analysis Tools
