Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Gcgem1Dvs
Name:	glucagon; endonuclease-mediated mutation 1, David V Serreze
MGI ID:	MGI:6455401
Synonyms:	Gcg1-29KO
Gene:	Gcg  Location: Chr2:62304874-62313994 bp, - strand  Genetic Position: Chr2, 35.85 cM
Alliance:	Gcgem1Dvs page

Strain of Origin:

NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ

Allele Type:    Endonuclease-mediated (Null/knockout) Mutation:    Intragenic deletion   Mutation details: CRISPR/Cas9 genome editing is used to create an in-frame deletion in exon 3 - specifically within the 87 nucleotides encoding the 1-29 residues. Founder male 18-1 was identified with a 91 bp deletion including 28 of the first 29 amino acids of the gene. (J:101977)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gcg Mutation:	32 strains or lines available

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	1 reference(s)