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Gene Expression Data
Assay Details
Assay
Reference: J:99792 Mari F, et al., CDKL5 belongs to the same molecular pathway of MeCP2 and it is responsible for the early-onset seizure variant of Rett syndrome. Hum Mol Genet. 2005 Jul 15;14(14):1935-46
Assay type: RNA in situ
MGI Accession ID: MGI:6455000
Gene symbol: Mecp2
Gene name: methyl CpG binding protein 2
Probe: Mecp2 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex Weak 3A
Specimen 3C: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: hippocampus Strong 3C
Specimen 3C inset: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus Present 3C inset
Specimen 3E: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: amygdala Strong 3E
TS28: cortical layer I Strong 3E
TS28: cortical layer II Strong 3E
TS28: cortical layer III Strong 3E
TS28: cortical layer IV Strong 3E
TS28: cortical layer V Strong 3E
TS28: cortical layer VI Strong 3E
TS28: dorsal lateral geniculate nucleus Strong 3E
TS28: hippocampus Strong 3E
TS28: piriform cortex Strong 3E
Specimen 3G: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cortical layer I Present 3G
TS28: cortical layer II Present 3G
TS28: cortical layer III Present 3G
TS28: cortical layer IV Present 3G
TS28: cortical layer V Present 3G
TS28: cortical layer VI Present 3G
Specimen 3I: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 3I
TS28: cerebellum external granule cell layer Weak 3I
TS28: cerebellum internal granule cell layer Weak 3I
Specimen 3K: postnatal day 10 (more )
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 3K
TS28: cerebellum external granule cell layer Weak 3K
TS28: cerebellum internal granule cell layer Weak 3K
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory