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Gene Expression Data
Assay Details
Assay
Reference: J:79619 Braybrook C, et al., Craniofacial expression of human and murine TBX22 correlates with the cleft palate and ankyloglossia phenotype observed in CPX patients. Hum Mol Genet. 2002 Oct 15;11(22):2793-804
Assay type: RNA in situ
MGI Accession ID: MGI:6454978
Gene symbol: Tbx22
Gene name: T-box 22
Probe: Tbx22 cDNA4
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 6A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: palatal shelf Present 6A

Specimen 6B: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Present Graded 6B Expression is strongest in cells immediately subjacent to the medial edge epithelium and is stronger medially than laterally.
TS21: oral epithelium Present 6B
TS21: palatal shelf epithelium Present 6B
TS21: tongue Present Regionally restricted 6B Expression is in the anterior region.

Specimen 6D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: tongue mesenchyme Strong Regionally restricted 6D Expression is in the ventral region at the base.
TS22: frenulum Strong 6D
TS22: tooth mesenchyme Present 6D
TS22: palatal shelf Weak 6D

Specimen 6E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: nasal septum Present Regionally restricted 6E Expression is at the base.

Specimen 6F: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: oral epithelium Very strong 6F
TS23: palatal shelf Present Regionally restricted 6F Expression is at the site of palatal shelf fusion.
TS23: palatal shelf epithelium Present Regionally restricted 6F Expression is at the disrupted epithelial seam.

Specimen 6G: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: nose Present Regionally restricted 6G Expression is in nasal cartilage.
TS25: nasal septum Present Regionally restricted 6G Expression is at the base.
TS25: face Present Regionally restricted 6G Expression is in glandular structures in the nose and face.
TS25: gland Present Regionally restricted 6G Expression is in glandular structures in the nose and face.
TS25: olfactory gland Present 6G
TS25: secondary palate Absent 6G

Specimen 6H: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: tooth mesenchyme Present 6H

Specimen 6I: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: tooth Present 6I

Specimen 6J: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: lung epithelium Present 6J

Specimen 6K: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: vibrissa follicle Present 6K


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory