Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:111788
Kiyozumi D, et al., Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects. Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11981-6
|
|
Assay type:
|
Immunohistochemistry
|
|
MGI Accession ID:
|
MGI:6454325
|
|
Gene symbol:
|
Frem1
|
|
Gene name:
|
Fras1 related extracellular matrix protein 1
|
|
Antibody:
|
Anti-QBRICK
|
|
Detection system:
|
colloidal gold
|
|
Assay notes:
|
Fixation with 1% glutaraldehyde, 4% paraformaldehyde, 2% glutaraldehyde. Embedded in epoxy.
|
|
|
Results
|
Specimen
S11A:
embryonic day 15.5; Frem2my/Frem2 +
(more  )
Specimen
S11A:
(close  )
|
Genetic Background:
|
involves: MY/HuLeJ * C57BL/6
|
|
Mutant Allele(s):
|
Frem2my/Frem2+
|
|
Age:
|
embryonic day 15.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
Other - See Notes
|
|
Embedding:
|
Resin/plastic
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS23: skin |
Present |
Regionally restricted |
S11A
|
Expression in lamina densa, and in subepidermal region of dermal mesenchyme. Expression often in close proximity to that of Fras1.
|
|
Analysis Tools