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Gene Expression Data
Assay Details
Assay
Reference: J:111788 Kiyozumi D, et al., Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects. Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11981-6
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6454323
Gene symbol: Frem1
Gene name: Fras1 related extracellular matrix protein 1
Antibody: Anti-QBRICK
Detection system: Alexa Fluor 488
Results
Specimen 4A my/+ left: embryonic day 13.5; Frem2my/Frem2+ (more )
Structure Level Pattern Image Note
TS21: back skin Present 4A my/+ left

Specimen 4A my/my left: embryonic day 13.5; Frem2my/Frem2my (more )
Structure Level Pattern Image Note
TS21: back skin Weak 4A my/my left Expression reduced in my/my mice at E13.5.

Specimen 4B my/+ left: embryonic day 17.5; Frem2my/Frem2+ (more )
Structure Level Pattern Image Note
TS25: back skin Present 4B my/+ left

Specimen 4B my/my left: embryonic day 17.5; Frem2my/Frem2my (more )
Structure Level Pattern Image Note
TS25: back skin Trace 4B my/my left Reduction in expression more prominent at later developmental stages.

Specimen 4C my/+ left: postnatal newborn; Frem2my/Frem2+ (more )
Structure Level Pattern Image Note
TS27: back skin Present 4C my/+ left

Specimen 4C my/my left: postnatal newborn; Frem2my/Frem2my (more )
Structure Level Pattern Image Note
TS27: back skin Trace 4C my/my left Reduction in expression more prominent at later developmental stages.

Specimen 4D eb/+ left: embryonic day 14.5; Grip1eb/Grip1+ (more )
Structure Level Pattern Image Note
TS22: back skin Present 4D eb/+ left

Specimen 4D eb/eb left: embryonic day 14.5; Grip1eb/Grip1eb (more )
Structure Level Pattern Image Note
TS22: back skin Weak 4D eb/eb left Expression reduced at E14.5

Specimen 4E eb/+ left: postnatal newborn; Grip1eb/Grip1+ (more )
Structure Level Pattern Image Note
TS27: back skin Present 4E eb/+ left

Specimen 4E eb/eb left: postnatal newborn; Grip1eb/Grip1eb (more )
Structure Level Pattern Image Note
TS27: back skin Trace 4E eb/eb left Expression almost absent at birth.

Specimen 5G +/- left: embryonic day 14.5; Frem1tm1Ksek/Frem1+ (more )
Structure Level Pattern Image Note
TS22: back skin Present 5G +/- left

Specimen 5G -/- left: embryonic day 14.5; Frem1tm1Ksek/Frem1tm1Ksek (more )
Structure Level Pattern Image Note
TS22: back skin Absent 5G -/- left No expression at basement membrane zone.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory