About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:53409 Murdoch JN, et al., Sequence and expression analysis of Nhlh1: a basic helix-loop-helix gene implicated in neurogenesis. Dev Genet. 1999;24(1-2):165-77
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6452589
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: anti-C-Isl-1 protein (K5)
Detection system: horseradish peroxidase
Results
Specimen 4F: embryonic day 10.5 (more )
Note: Double labeled: brown - Isl1; blue - Nhlh1 (assay MGI:6452588).
Structure Level Pattern Image Note
TS17: neural tube Strong Regionally restricted 4F Strong expression in ventrolateral region of neural tube. Expression also in region of dorsal neural tube, marking subpopularion of dorsal sensory interneurons. Expression in a few cells more medially, within Nhlh1 expression domain, likely to represent motor neurons.
TS17: dorsal root ganglion Present 4F
Specimen 4G: embryonic day 10.5 (more )
Note: Double labeled: brown - Isl1; blue - Nhlh1 (assay MGI:6452588).
Structure Level Pattern Image Note
TS17: neural tube Strong Regionally restricted 4G Strong expression in ventrolateral region of neural tube. Expression also in region of dorsal neural tube, marking subpopularion of dorsal sensory interneurons. Expression in a few cells more medially, within Nhlh1 expression domain, likely to represent motor neurons.
TS17: dorsal root ganglion Present 4G
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory