Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Ndrg1tm1(cre/ERT2)Myan
Name:	N-myc downstream regulated gene 1; targeted mutation 1, Motoko Yanagita
MGI ID:	MGI:6451756
Synonyms:	Ndrg1CreERT2
Gene:	Ndrg1  Location: Chr15:66801167-66841489 bp, - strand  Genetic Position: Chr15, 29.3 cM, cytoband D3
Alliance:	Ndrg1tm1(cre/ERT2)Myan page

Germline Transmission:	Earliest citation of germline transmission: J:261876
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6J

Allele Type:    Targeted (Inducible, Null/knockout, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Ndrg1tm1(cre/ERT2)Myan expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Ndrg1 (MGI:1341799)   Mutation details: The targeting vector was designed to insert Cre/ERT2 cassette, polyA tail, and loxP-flanked PGK-Neo cassette in the opposite transcriptional orientation to the first exon of the Ndrg1 gene at the position of the initiation codon. The knock-in allele disrupted the first exon, thereby deleting the expression of Ndrg1. (J:261876)

Activity:	Tissue activity of this recombinase allele
Driver:	Ndrg1 (mouse) Summary of all recombinase alleles driven by Ndrg1. Comparative matrix view of recombinase activities Alliance mouse Ndrg1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ndrg1 Mutation:	27 strains or lines available

Original:	J:261876 Endo T, et al., Exploring the origin and limitations of kidney regeneration. J Pathol. 2015 Jun;236(2):251-63
All:	11 reference(s)