Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Tacr3tm1.1(cre/GFP)Rpa
Name:	tachykinin receptor 3; targeted mutation 1.1, Richard D Palmiter
MGI ID:	MGI:6451481
Gene:	Tacr3  Location: Chr3:134534768-134640340 bp, + strand  Genetic Position: Chr3, 62.47 cM, cytoband H2
Alliance:	Tacr3tm1.1(cre/GFP)Rpa page

Germline Transmission:	Earliest citation of germline transmission: J:101977
Parent Cell Line:	G4 (ES Cell)
Strain of Origin:	(129S6/SvEvTac x C57BL/6NCrl)F1

Allele Type:    Targeted (Recombinase, Reporter) Mutation:    Insertion   Tacr3tm1.1(cre/GFP)Rpa expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Tacr3 (MGI:892968)   Mutation details: A cassette encoding IRES-mnCre:GFP (an internal ribosome entry sequence (IRES), a Myc-tag and nuclear localization signals at the N-terminus of Cre recombinase, which is fused to green fluorescent protein followed by a SV40 polyadenylation sequence) was inserted just 3' of the termination codon in the last coding exon of the Tacr3 gene via homologous recombination. The neomycin cassette was excised through crosses with animals broadly expressing Flp recombinase. (J:101977)

Activity:	Tissue activity of this recombinase allele
Driver:	Tacr3 (mouse) Summary of all recombinase alleles driven by Tacr3. Alliance mouse Tacr3 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tacr3 Mutation:	34 strains or lines available

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	1 reference(s)