About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:270210 Loo L, et al., Single-cell transcriptomic analysis of mouse neocortical development. Nat Commun. 2019 Jan 11;10(1):134
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6451471
Gene symbol: Dkk3
Gene name: dickkopf WNT signaling pathway inhibitor 3
Antibody: Anti-Dkk3 (ab2459)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 3c: embryonic day 14.5 (more )
Note: Triple labeled: green - Dkk3; blue - Sox2 (assay MGI:6451482); red - Reln (assay MGI:6451465).
Structure Level Pattern Image Note
TS22: cortical hem Present 3e , 3d , 3c
TS22: cerebral cortex Present Graded 3d , 3c , 3e Expression was detected in an intermediate population of cells between immature progenitors of the cortical hem and mature Cajal-Retzius cells. Many of these cells expressed Dkk3, Sox2, and Reln.
Specimen 3f: embryonic day 14.5 (more )
Note: Triple labeled: green - Dkk3; blue - Eomes (assay MGI:6451480); red - Reln (assay MGI:6451465).
Structure Level Pattern Image Note
TS22: cortical hem Present 3g , 3h , 3f
TS22: cerebral cortex Present Graded 3h , 3f , 3g Expression was detected in an intermediate population of cells between immature progenitors of the cortical hem and mature Cajal-Retzius cells. Many cells expressed a mixture of Dkk3, Eomes, and Reln.
Specimen S20a: embryonic day 14.5 (more )
Note: Triple labeled: green - Dkk3; blue - Eomes (assay MGI:6451480); red - Reln (assay MGI:6451465).
Structure Level Pattern Image Note
TS22: cerebral cortex Present Regionally restricted S20d , S20a , S20b Expression was detected in layer I. Cells were noted (arrow) that expressed both Dkk3 and Reln.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory