Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Adcyap1r1tm1.1(cre/GFP)Rpa
Name:	adenylate cyclase activating polypeptide 1 receptor 1; targeted mutation 1.1, Richard D Palmiter
MGI ID:	MGI:6451460
Gene:	Adcyap1r1  Location: Chr6:55428963-55478436 bp, + strand  Genetic Position: Chr6, 27.38 cM, cytoband B3
Alliance:	Adcyap1r1tm1.1(cre/GFP)Rpa page

Germline Transmission:	Earliest citation of germline transmission: J:331457
Parent Cell Line:	G4 (ES Cell)
Strain of Origin:	(129S6/SvEvTac x C57BL/6NCrl)F1

Allele Type:    Targeted (Recombinase, Reporter) Mutation:    Insertion   Adcyap1r1tm1.1(cre/GFP)Rpa expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Adcyap1r1 (MGI:108449)   Mutation details: A cassette encoding IRES-mnCre:GFP (an internal ribosome entry sequence (IRES), a Myc-tag and nuclear localization signals at the N-terminus of Cre recombinase, which is fused to green fluorescent protein followed by a SV40 polyadenylation sequence) was inserted just 3' of the termination codon in the last coding exon of the Adcyap1r1 gene via homologous recombination. The neomycin cassette was excised through crosses with animals broadly expressing Flp recombinase. (J:101977)

Activity:	Tissue activity of this recombinase allele
Driver:	Adcyap1r1 (mouse) Summary of all recombinase alleles driven by Adcyap1r1. Comparative matrix view of recombinase activities Alliance mouse Adcyap1r1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Adcyap1r1 Mutation:	34 strains or lines available

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	2 reference(s)