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Gene Expression Data
Assay Details
Assay
Reference: J:147670 Done SC, et al., Nephrin is involved in podocyte maturation but not survival during glomerular development. Kidney Int. 2008 Mar;73(6):697-704
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6450790
Gene symbol: Cldn3
Gene name: claudin 3
Results
Specimen 4a Claudin 3 Nphs1+/+: embryonic day 18.5 (more )
Note: Double labeled: green - Cldn3; red - Synpo (assay MGI:6450785).
Structure Level Pattern Image Note
TS26: glomerular tuft Present Regionally restricted 4a Claudin 3 Nphs1+/+ , 4a Nphs1+/+ Merge Expression mainly in non-podocyte regions.
Specimen 4a Claudin 3 Nphs1-/-: embryonic day 18.5; Nphs1tm1Ktry/Nphs1tm1Ktry (more )
Note: Double labeled: green - Cldn3; red - Synpo (assay MGI:6450785).
Structure Level Pattern Image Note
TS26: glomerular capillary system Strong 4a Claudin 3 Nphs1-/- , 4a Nphs1-/- Merge Strong expression in glomerular capillaries.
Specimen 4b Nphs1+/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: glomerular tuft Trace Scattered 4b Nphs1+/+ Only scattered expression observed in glomeruli.
Specimen 4b Nphs1-/-: embryonic day 18.5; Nphs1tm1Ktry/Nphs1tm1Ktry (more )
Structure Level Pattern Image Note
TS26: glomerular tuft Present Regionally restricted 4b Nphs1-/- Expression at junction-like structures between adjacent podocytes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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