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Gene Expression Data
Assay Details
Assay
Reference: J:147670 Done SC, et al., Nephrin is involved in podocyte maturation but not survival during glomerular development. Kidney Int. 2008 Mar;73(6):697-704
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6450782
Gene symbol: Wt1
Gene name: WT1 transcription factor
Antibody: anti-WT-1
Results
Specimen 2a Nphs1+/+: embryonic day 18.5 (more )
Note: Triple labeled: green - Wt1; red - BrdU; blue - DAPI.
Structure Level Pattern Image Note
TS26: glomerular tuft Present Regionally restricted 2a Nphs1+/+ Merge , 2a Nphs1+/+ WT1 Authors report that proliferation events are occurring in other glomerular cell types, but not in podocytes.
Specimen 2a Nphs1-/-: embryonic day 18.5; Nphs1tm1Ktry/Nphs1tm1Ktry (more )
Note: Triple labeled: green - Wt1; red - BrdU; blue - DAPI.
Structure Level Pattern Image Note
TS26: glomerular tuft Present Regionally restricted 2a Nphs1-/- Merge , 2a Nphs1-/- WT1 Authors report that proliferation events are occurring in other glomerular cell types, but not in podocytes.
Specimen 3 WT-1 Nphs1+/+: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: glomerular tuft Present 3_WT1 Nphs1+/+
Specimen 3 WT-1 Nphs1-/-: embryonic day 18.5; Nphs1tm1Ktry/Nphs1tm1Ktry (more )
Structure Level Pattern Image Note
TS26: glomerular tuft Present 3_WT1 Nphs1-/- Absence of nephrin did not affect expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/28/2026
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