Slc9a3tm1.1(cre/ERT2)Niba
Targeted Allele Detail
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Symbol: |
Slc9a3tm1.1(cre/ERT2)Niba |
Name: |
solute carrier family 9 (sodium/hydrogen exchanger), member 3; targeted mutation 1.1, Nick Barker |
MGI ID: |
MGI:6450711 |
Synonyms: |
Slc9a3-eGFP-IRES-creERT2 |
Gene: |
Slc9a3 Location: Chr13:74269576-74317561 bp, + strand Genetic Position: Chr13, 40.15 cM
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Alliance: |
Slc9a3tm1.1(cre/ERT2)Niba page
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Germline Transmission: |
Earliest citation of germline transmission:
J:292580
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Inducible, Null/knockout, Recombinase, Reporter) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Slc9a3tm1.1(cre/ERT2)Niba expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Slc9a3 (MGI:105064) |
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Mutation details: The following construct was inserted immediately after the ATG start codon: the EGFP fluorescent reporter gene, IRES sequence, a cre-ERT2 fusion gene, and a loxP site flanked neomycin resistance gene cassette. The neo cassette was removed through subsequent cre-mediated recombination.
(J:292580)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Slc9a3
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Slc9a3 Mutation: |
45 strains or lines available
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Original: |
J:292580 Tan SH, et al., AQP5 enriches for stem cells and cancer origins in the distal stomach. Nature. 2020 Feb;578(7795):437-443 |
All: |
1 reference(s) |
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