Tg(Glp1r-mApple)1Dlgr
Transgene Detail
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| Symbol: |
Tg(Glp1r-mApple)1Dlgr |
| Name: |
transgene insertion 1, Devon L Graham |
| MGI ID: |
MGI:6450159 |
| Synonyms: |
GLP-1R-mApple |
| Transgene: |
Tg(Glp1r-mApple)1Dlgr Location: unknown
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| Alliance: |
Tg(Glp1r-mApple)1Dlgr page
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| Transgene Type: |
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Transgenic (Reporter) |
| Mutation: |
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Insertion
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Mutation details: The BAC clone (bMQ458o12) contains the Glp1r gene flanked by 6 exons of the Dnahc8 gene at the 5' end and the first two exons of the Umod1 gene at the 3' end. A vector containing an optimized Kozak translation initiation sequence, a beta-globin poly-adenylation signal (BpA), the mApple fluorescent reporter, and an FRT-flanked kanamycin/neomycin resistance cassette is inserted into the start codon of the Glp1r gene within the BAC clone. The FRT-flanked cassettes were removed by transient transfection of a FLP recombinase-expressing plasmid.
(J:292440)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:292440 Reddy IA, et al., Glucagon-like peptide 1 receptor activation regulates cocaine actions and dopamine homeostasis in the lateral septum by decreasing arachidonic acid levels. Transl Psychiatry. 2016 May 17;6:e809 |
| All: |
3 reference(s) |
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Analysis Tools
