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Gene Expression Data
Assay Details
Assay
Reference: J:261409 Xu M, et al., Generation and characterization of Lhx3(GFP) reporter knockin and Lhx3(loxP) conditional knockout mice. Genesis. 2018 Apr;56(4):e23098
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6449860
Gene symbol: Lhx3
Gene name: LIM homeobox protein 3
Antibody: anti-LHX3 (ab14555)
Detection system: Secondary antibody
Results
Specimen 2a: embryonic day 14.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS22: cochlea Absent 2a
Specimen 2a bottom: embryonic day 14.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS22: cochlea Absent 2a bottom
Specimen 2b: embryonic day 15.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS23: cochlea Present Regionally restricted 2b Expression is in the inner hair cells of the basal turn.
Specimen 2b bottom: embryonic day 15.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS23: cochlea Present Regionally restricted 2b bottom Expression is in the inner hair cells of the basal turn.
Specimen 2c: embryonic day 16.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS24: organ of Corti Present Regionally restricted 2c Expression is in inner and outer hair cells at the basal and basal-middle turns.
Specimen 2c bottom: embryonic day 16.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS24: organ of Corti Present Regionally restricted 2c bottom Expression is in inner and outer hair cells at the basal and basal-middle turns.
Specimen 2d: embryonic day 17.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS25: organ of Corti Present Regionally restricted 2d Expression is in inner and outer hair cells at the basal and basal-middle turns.
Specimen 2d Ap-Mid: embryonic day 17.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS25: organ of Corti Present Regionally restricted 2d Ap-Mid Expression is in inner and outer hair cells at the basal and basal-middle turns.
Specimen 2d Ba-Mid: embryonic day 17.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS25: organ of Corti Present Regionally restricted 2d Ba-Mid Expression is in inner and outer hair cells at the basal and basal-middle turns.
Specimen 2d Base: embryonic day 17.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS25: organ of Corti Present Regionally restricted 2d Base Expression is in inner and outer hair cells at the basal and basal-middle turns.
Specimen 2e: postnatal day 0; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 2e Expression is in inner and outer hair cells at the basal and basal-middle turns.
Specimen 2e Ap-Mid: postnatal day 0; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 2e Ap-Mid Expression is in inner and outer hair cells at the basal and basal-middle turns.
Specimen 2e Ba-Mid: postnatal day 0; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 2e Ba-Mid Expression is in inner and outer hair cells at the basal and basal-middle turns.
Specimen 2e Base: postnatal day 0; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS27: organ of Corti Present Regionally restricted 2e Base Expression is in inner and outer hair cells at the basal and basal-middle turns.
Specimen 3a: embryonic day 13.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS21: cochlea Absent 3a
TS21: semicircular canal Absent 3a
Specimen 3a PC: embryonic day 13.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS21: semicircular canal Absent 3a PC Expression is absent including the hair cells of the posterior cristae (shown).
Specimen 3a U: embryonic day 13.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS21: semicircular canal Absent 3a U Expression is absent including the macule of utricle (shown).
Specimen 3a S: embryonic day 13.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS21: semicircular canal Absent 3a S Expression is absent including the saccule (shown).
Specimen 3b: embryonic day 14.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS22: vestibular labyrinth Present Regionally restricted 3b Expression is in the hair cells of the posterior cristae, macule of utricle, and saccule.
TS22: macula of saccule Present Regionally restricted 3b Expression is in the hair cells.
TS22: macula of utricle Present Regionally restricted 3b Expression is in the hair cells.
TS22: semicircular canal Present Regionally restricted 3b Expression is in the hair cells of the posterior cristae.
Specimen 3b PC: embryonic day 14.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS22: semicircular canal Present Regionally restricted 3b PC Expression is in the hair cells of the posterior cristae.
Specimen 3b U: embryonic day 14.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS22: macula of utricle Present Regionally restricted 3b U Expression is in the hair cells.
Specimen 3c: embryonic day 15.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS23: vestibular labyrinth Present Regionally restricted 3c Expression is in the hair cells of the posterior cristae, macule of utricle, and saccule.
TS23: macula of saccule Present Regionally restricted 3c Expression is in the hair cells.
TS23: macula of utricle Present Regionally restricted 3c Expression is in the hair cells.
TS23: semicircular canal Present Regionally restricted 3c Expression is in the hair cells of the posterior cristae.
Specimen 3c PC: embryonic day 15.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS23: semicircular canal Present Regionally restricted 3c PC Expression is in the hair cells of the posterior cristae.
Specimen 3c U: embryonic day 15.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS23: macula of utricle Present Regionally restricted 3c U Expression is in the hair cells.
Specimen 3c S: embryonic day 15.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS23: macula of saccule Present Regionally restricted 3c S Expression is in the hair cells.
Specimen 4a: postnatal day 4; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS28: retina Absent 4a
Specimen 4b: postnatal day 5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Weak Regionally restricted 4b Expression is in differentiating bipolar cells.
Specimen 4c: postnatal day 9; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Strong Regionally restricted 4c' , 4c Expression is in the bipolar cells.
Specimen 4d: postnatal day 15; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Strong Regionally restricted 4d' , 4d Expression is in the bipolar cells.
Specimen 4e: postnatal day 30; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS28: retina inner nuclear layer Weak Regionally restricted 4e , 4e' Expression is in the bipolar cells.
Specimen 4f: embryonic day 13.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS21: spinal cord ventral horn Present Regionally restricted 4f , 4f' Expression is in motor neurons and in ventral interneuron group 2.
Specimen 4g: embryonic day 14.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS22: spinal cord ventral horn Present Regionally restricted 4g Expression is in motor neurons and in ventral interneuron group 2.
Specimen 4h: embryonic day 15.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS23: spinal cord ventral horn Present Regionally restricted 4h Expression is in motor neurons and in ventral interneuron group 2.
Specimen 4i: embryonic day 16.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS24: spinal cord ventral horn Present Regionally restricted 4i Expression is in motor neurons and in ventral interneuron group 2.
Specimen 4j: embryonic day 17.5; Lhx3tm1.2Gan/Lhx3+ (more )
Note: Double labeled: red - Lhx3 protein; green - Lhx3 reporter (assay MGI:6449725).
Structure Level Pattern Image Note
TS25: spinal cord ventral horn Present Regionally restricted 4j Expression is in motor neurons and in ventral interneuron group 2.
Specimen 5a: embryonic day 16.6; Lhx3tm1.1Gan/Lhx3+, Tg(CMV-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: spinal cord ventral horn Present Regionally restricted 5a Expression is in motor neurons and in ventral interneuron group 2.
Specimen 5a': embryonic day 16.6; Lhx3tm1.1Gan/Lhx3tm1.1Gan, Tg(CMV-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: spinal cord ventral horn Absent 5a'
Specimen 5b: embryonic day 16.6; Lhx3tm1.1Gan/Lhx3+, Tg(CMV-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: cochlea Present Regionally restricted 5b Expression is in hair cells.
Specimen 5b': embryonic day 16.6; Lhx3tm1.1Gan/Lhx3tm1.1Gan, Tg(CMV-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: cochlea Absent 5b'
Specimen 5c: embryonic day 16.6; Lhx3tm1.1Gan/Lhx3+, Tg(CMV-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: semicircular canal Present Regionally restricted 5c Expression is in hair cells of the cristae.
Specimen 5c': embryonic day 16.6; Lhx3tm1.1Gan/Lhx3tm1.1Gan, Tg(CMV-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: semicircular canal Absent 5c'
Specimen 5d: embryonic day 16.6; Lhx3tm1.1Gan/Lhx3+, Tg(CMV-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: macula of saccule Present Regionally restricted 5d Expression is in hair cells.
Specimen 5d': embryonic day 16.6; Lhx3tm1.1Gan/Lhx3tm1.1Gan, Tg(CMV-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: macula of saccule Absent 5d'
Specimen 5e: embryonic day 16.6; Lhx3tm1.1Gan/Lhx3+, Tg(CMV-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: macula of utricle Present Regionally restricted 5e Expression is in hair cells.
Specimen 5e': embryonic day 16.6; Lhx3tm1.1Gan/Lhx3tm1.1Gan, Tg(CMV-cre)1Cgn/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: macula of utricle Absent 5e'
Specimen not shown: postnatal adult; Lhx3tm1.2Gan/Lhx3+ (more )
Structure Level Pattern Image Note
TS28: crista ampullaris Present Expression is in the hair cells.
TS28: macula of saccule Present Expression is in the hair cells.
TS28: macula of utricle Present Expression is in the hair cells.
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03/18/2025
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