Gene Expression Data
Assay Details
Assay
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Reference:
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J:178818
Wang B, et al., Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development. Development. 2011 Oct;138(20):4487-97
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6449833
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Gene symbol:
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Skor2
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Gene name:
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SKI family transcriptional corepressor 2
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Probe:
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Skor2 cDNA1
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
3A:
embryonic day 15.0
(more )
Specimen
3A:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 15.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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Structure |
Level |
Pattern |
Image |
Note |
TS23: cerebellum |
Strong |
Regionally restricted |
3B
,
3A
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Expression was strong in the central region of the cerebellum where primitive Purkinje cells are located.
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Specimen
3C:
postnatal day 0
(more )
Specimen
3C:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
|
Structure |
Level |
Pattern |
Image |
Note |
TS27: cerebellum Purkinje cell layer |
Present |
Non-Uniform |
3C
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Predominant expression was detected in Purkinje cell layers at P0. Higher levels of expression were observed in the rostral lobes compared with caudal lobes.
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Specimen
3D:
postnatal month 2
(more )
Specimen
3D:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal month 2
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
5A Control:
postnatal day 0
(more )
Specimen
5A Control:
(close )
Genetic Background:
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Not Specified
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Age:
|
postnatal day 0
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Sex:
|
Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
S3:
postnatal month 2
(more )
Specimen
S3:
(close )
Genetic Background:
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Not Specified
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Age:
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postnatal month 2
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Cryosection
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Structure |
Level |
Pattern |
Image |
Note |
TS28: brain |
Present |
Regionally restricted |
S3
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Expression was detected exclusively in the cerebellum.
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TS28: cerebellum |
Present |
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S3
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