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Gene Expression Data
Assay Details
Assay
Reference: J:223183 Yang T, et al., Analysis of PRICKLE1 in human cleft palate and mouse development demonstrates rare and common variants involved in human malformations. Mol Genet Genomic Med. 2014 Mar;2(2):138-51
Assay type: RNA in situ
MGI Accession ID: MGI:6449682
Gene symbol: Fgf10
Gene name: fibroblast growth factor 10
Probe: Fgf10 cDNA10
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 5C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf Present 5C
Specimen 5C': embryonic day 13.5 (more )
Note: anterior coronal section
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Present 5C' Expression is seen in the anterior palate.
TS21: palatal shelf epithelium Absent 5C'
Specimen 5C'': embryonic day 13.5 (more )
Note: posterior coronal section
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Absent 5C'' Expression is seen in the anterior (but not posterior) palate.
TS21: palatal shelf epithelium Absent 5C''
Specimen 5D: embryonic day 13.5; Prickle1m2Ingm/Prickle1m2Ingm (more )
Structure Level Pattern Image Note
TS21: palatal shelf Present 5D Expression is unaffected in the mutant.
Specimen 5D': embryonic day 13.5; Prickle1m2Ingm/Prickle1m2Ingm (more )
Note: anterior coronal section
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Present 5D' Expression is seen in the anterior palate; it is unaffected in the mutant.
TS21: palatal shelf epithelium Absent 5D'
Specimen 5D'': embryonic day 13.5; Prickle1m2Ingm/Prickle1m2Ingm (more )
Note: posterior coronal section
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Absent 5D'' As in wild type, expression is seen in the anterior (but not posterior) palate.
TS21: palatal shelf epithelium Absent 5D''
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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