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Gene Expression Data
Assay Details
Assay
Reference: J:223183 Yang T, et al., Analysis of PRICKLE1 in human cleft palate and mouse development demonstrates rare and common variants involved in human malformations. Mol Genet Genomic Med. 2014 Mar;2(2):138-51
Assay type: RNA in situ
MGI Accession ID: MGI:6449681
Gene symbol: Wnt5a
Gene name: wingless-type MMTV integration site family, member 5A
Probe: Wnt5a probe22
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 5A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: palatal shelf Present 5A
Specimen 5A': embryonic day 13.5 (more )
Note: anterior coronal section
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Present 5A' Expression is seen in the anterior palate mesenchyme.
TS21: palatal shelf epithelium Absent 5A'
Specimen 5A'': embryonic day 13.5 (more )
Note: posterior coronal section
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Present Regionally restricted 5A'' Expression is seen in the posterior tip of the palate.
TS21: palatal shelf epithelium Absent 5A''
Specimen 5B: embryonic day 13.5; Prickle1m2Ingm/Prickle1m2Ingm (more )
Structure Level Pattern Image Note
TS21: palatal shelf Present 5B Expression is unaffected in the mutant.
Specimen 5B': embryonic day 13.5; Prickle1m2Ingm/Prickle1m2Ingm (more )
Note: anterior coronal section
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Present 5B' Expression is seen in the anterior palate mesenchyme; it is unaffected in the mutant.
TS21: palatal shelf epithelium Absent 5B'
Specimen 5B'': embryonic day 13.5; Prickle1m2Ingm/Prickle1m2Ingm (more )
Note: posterior coronal section
Structure Level Pattern Image Note
TS21: palatal shelf mesenchyme Present Regionally restricted 5B'' Expression is seen in the posterior tip of the palate; it is unaffected in the mutant.
TS21: palatal shelf epithelium Absent 5B''
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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