Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Lamp5em1Atai
Name:	lysosomal-associated membrane protein family, member 5; endonuclease-mediated mutation 1, Atsu Aiba
MGI ID:	MGI:6449112
Synonyms:	Lamp5em1Okab
Gene:	Lamp5  Location: Chr2:135894159-135911837 bp, + strand  Genetic Position: Chr2, 67.26 cM, cytoband G1
Alliance:	Lamp5em1Atai page

Strain of Origin:

C57BL/6J

Allele Type:    Endonuclease-mediated (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A deletion spanning from the middle of exon 2 to the 3' end of intron 5 with a 3-base insertion. The mutation resulted in the in-frame fusion of the 5' half of exon 2 and the last exon, and the loss of most of the LAMP5 protein other than the signal peptide. (J:291365)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Lamp5 Mutation:	28 strains or lines available

Original:	J:291365 Koebis M, et al., LAMP5 in presynaptic inhibitory terminals in the hindbrain and spinal cord: a role in startle response and auditory processing. Mol Brain. 2019 Mar 12;12(1):20
All:	1 reference(s)