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Gene Expression Data
Assay Details
Assay
Reference: J:219234 Wang J, et al., FGF signaling is required for anterior but not posterior specification of the murine liver bud. Dev Dyn. 2015 Mar;244(3):431-43
Assay type: RNA in situ
MGI Accession ID: MGI:6446880
Gene symbol: Fgfr4
Gene name: fibroblast growth factor receptor 4
Probe: Fgfr4 cDNA6
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1U: embryonic day 8.0 (more )
Note: 3-4 somite stage embryo, prior to liver bud induction
Structure Level Pattern Image Note
TS12: gut endoderm Absent 1U No or weak expression is observed in a subset of prehepatic/hepatic endoderm cells.
Specimen 1V: embryonic day 8.0 (more )
Note: 5-6 somite stage embryo, prior to liver bud induction
Structure Level Pattern Image Note
TS12: gut endoderm Weak Single cells 1V Weak expression is observed in a subset of prehepatic/hepatic endoderm cells.
Specimen 1W: embryonic day 8.0 (more )
Note: 7-8 somite stage embryo, liver bud induction initiated
Structure Level Pattern Image Note
TS12: foregut diverticulum Weak Single cells 1W Weak expression is observed in a subset of prehepatic/hepatic endoderm cells.
Specimen 1X: embryonic day 8.5 (more )
Note: 9-11 somite stage embryo, anterior liver bud formed
Structure Level Pattern Image Note
TS13: foregut-midgut junction endoderm Present Patchy 1X Patchy expression is seen in the early liver bud.
Specimen 1Y: embryonic day 9.0 (more )
Note: 12-13 somite stage embryo, posterior liver bud formed
Structure Level Pattern Image Note
TS14: hepatic primordium Present Patchy 1Y Patchy expression is seen in the early liver bud.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory