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Gene Expression Data
Assay Details
Assay
Reference: J:248983 Varadarajan SG, et al., Netrin1 establishes multiple boundaries for axon growth in the developing spinal cord. Dev Biol. 2017 Oct 1;430(1):177-187
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6446811
Gene symbol: Ntn1
Gene name: netrin 1
Results
Specimen 2D: embryonic day 10.5; Ntn1Gt(ST629)Byg/Ntn1+ (more )
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 2D Broad expression in spinal cord. Low levels of expression in ventricular zone. Expression on pial surface at circumference of spinal cord. Expression excluded from dorsal-most spinal cord.

Specimen 2J: embryonic day 11.5; Ntn1Gt(ST629)Byg/Ntn1+ (more )
Structure Level Pattern Image Note
TS19: future spinal cord Present Regionally restricted 2J Expression on pial surface ventral to dorsal root entry zone (DREZ) as well as commissural axons.

Specimen 2N: embryonic day 12.5; Ntn1Gt(ST629)Byg/Ntn1+ (more )
Structure Level Pattern Image Note
TS20: spinal cord ventricular layer Present Graded 2N
TS20: spinal cord Present Regionally restricted 2N Expression on pial surface and in commissural axons which have resolved into medial and lateral fascicles.

Specimen 3E: embryonic day 10.5; Ntn1Gt(ST629)Byg/Ntn1+ (more )
Note: Double labeled: red - Ntn1; green - neurofilament.
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 3E Expression on pial surface coincident with position of ventrally-directed axons growth in mantle layer.

Specimen 3F: embryonic day 10.5; Ntn1Gt(ST629)Byg/Ntn1+ (more )
Note: Double labeled: red - Ntn1; green - neurofilament.
Structure Level Pattern Image Note
TS17: future spinal cord Present Regionally restricted 3F ntn1 , 3F Expression on pial surface coincident with position of ventrally-directed axons growth in mantle layer.

Specimen 4B: embryonic day 11.5; Ntn1Gt(ST629)Byg/Ntn1+ (more )
Note: Triple labeled: red - Ntn1; blue - Cntn2 (assay MGI:6446808); green - neurofilament.
Structure Level Pattern Image Note
TS19: neural tube floor plate Present 4B , 4B ntn1

Specimen 4I: embryonic day 12.5 (more )
Note: Double labeled: red - Ntn1; green - neurofilament.
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted 4I Expression on pial surface of ventral spinal cord.

Specimen 4J: embryonic day 12.5 (more )
Note: Double labeled: red - Ntn1; green - neurofilament.
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted 4J Expression on pial surface of dorsal spinal cord ventral to dorsal root entry zone (DREZ).

Specimen 4K: embryonic day 12.5 (more )
Note: Double labeled: red - Ntn1; green - neurofilament.
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted 4K , 4K ntn1 Expression on pial surface of spinal cord.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/22/2024
MGI 6.24
The Jackson Laboratory