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Gene Expression Data
Assay Details
Assay
Reference: J:231234 Luna RL, et al., Placental growth factor deficiency is associated with impaired cerebral vascular development in mice. Mol Hum Reprod. 2016 Feb;22(2):130-42
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6445623
Gene symbol: Vegfa
Gene name: vascular endothelial growth factor A
Antibody: anti-VEGF (ab46162)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2A FB left: embryonic day 12.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS20: lateral ventricle Present 2A FB VEGF left
Specimen 2A FB right: embryonic day 12.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS20: diencephalon Present 2A FB VEGF right
Specimen 2A MB left: embryonic day 12.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS20: maxillary process Present 2A MB VEGF left
Specimen 2A MB right: embryonic day 12.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS20: trigeminal ganglion Present 2A MB VEGF right
Specimen 2A HB left: embryonic day 12.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS20: brain vascular element Strong Regionally restricted 2A HB VEGF left Expressed in endothelial cells in the hindbrain vessels of marginal layer.
TS20: hindbrain marginal layer Strong Regionally restricted 2A HB VEGF left Expressed in endothelial cells in the hindbrain vessels of marginal layer.
Specimen 2A HB right: embryonic day 12.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS20: hindbrain roof Present 2A HB VEGF right More highly expressed than PGF.
Specimen 2B FB left: embryonic day 14.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS22: forebrain vascular element Present 2B FB VEGF left Expressed in the superior dural venous sinus.
Specimen 2B FB right: embryonic day 14.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS22: corpus striatum Present 2B FB VEGF right
TS22: lateral ventricle Present 2B FB VEGF right
Specimen 2B MB left: embryonic day 14.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS22: diencephalon Present 2B MB VEGF left
Specimen 2B MB right: embryonic day 14.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS22: trigeminal ganglion Present 2B MB VEGF right
Specimen 2B HB left: embryonic day 14.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS22: hindbrain venous dural sinus Present 2B HB VEGF left Predominantly expressed in the transverse dural venous sinus.
Specimen 2B HB right: embryonic day 14.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS22: 4th ventricle Present 2B HB VEGF right Predominantly expressed.
Specimen 3A FB left: embryonic day 16.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS24: forebrain vascular element Present 3A FB VEGF left Significantly less expression than Pgf.
TS24: telencephalon Present 3A FB VEGF left Significantly less expression than Pgf.
Specimen 3A FB right: embryonic day 16.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS24: lateral ventricle Present 3A FB VEGF right Less expression than Pgf.
Specimen 3A MB left: embryonic day 16.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS24: midbrain vascular element Strong Regionally restricted 3A MB VEGF left Expressed in the transverse dural venous sinus.
Specimen 3A MB right: embryonic day 16.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS24: midbrain vascular element Present Regionally restricted 3A MB VEGF right Expressed in the mesencephalic vesicle.
Specimen 3A HB left: embryonic day 16.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS24: cerebellum Present 3A HB VEGF left Highest expression.
Specimen 3A HB right: embryonic day 16.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS24: brain vascular element Present Regionally restricted 3A HB VEGF right Highest expression in vessels of the primitive cerebellum.
TS24: cerebellum Present Regionally restricted 3A HB VEGF right Highest expression in vessels of the primitive cerebellum.
Specimen 3B FB left: embryonic day 18.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS26: cerebral hemisphere white matter Present Regionally restricted 3B FB VEGF left Expressed in the vessels of the white matter.
TS26: forebrain vascular element Present Regionally restricted 3B FB VEGF left Expressed in the vessels of the white matter.
Specimen 3B FB right: embryonic day 18.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS26: superior horn of lateral ventricle Present 3B FB VEGF right
Specimen 3B MB left: embryonic day 18.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS26: hippocampus Present Regionally restricted 3B MB VEGF left Expressed in the vessels in the hippocampus.
TS26: midbrain vascular element Present Regionally restricted 3B MB VEGF left Expressed in the vessels in the hippocampus.
Specimen 3B MB right: embryonic day 18.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS26: brain venous system Present Regionally restricted 3B MB VEGF right Expressed in the transverse dural venous sinus.
Specimen 3B HB left: embryonic day 18.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS26: cerebellum Present Regionally restricted 3B HB VEGF left Greater expression than Pgf.
Specimen 3B HB right: embryonic day 18.5 (more )
Note: Double labeled: green - Vegfa; red - Pecam1 (assay MGI:6445625).
Structure Level Pattern Image Note
TS26: posterior semicircular canal Present 3B HB VEGF right
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory