About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:231312 Baardman ME, et al., Common arterial trunk and ventricular non-compaction in Lrp2 knockout mice indicate a crucial role of LRP2 in cardiac development. Dis Model Mech. 2016 Apr 1;9(4):413-25
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6444472
Gene symbol: Tfap2a
Gene name: transcription factor AP-2, alpha
Results
Specimen 4F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: trunk mesenchyme derived from neural crest Strong Regionally restricted 4F Expressed in cells around the 6th pharyngeal arch arteries. Not expressed in the flow divider.
Specimen 4H: embryonic day 10.5; Lrp2tm1Her/Lrp2tm1Her (more )
Structure Level Pattern Image Note
TS17: trunk mesenchyme derived from neural crest Present Regionally restricted 4H Neural crest cells in the left (pulmonary) side already reached the neural crest cells in the endocardial outflow tract.
Specimen 4J: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: trunk mesenchyme derived from neural crest Present Regionally restricted 4J Expressed in cells around the 6th pharyngeal arch arteries.
Specimen 4L: embryonic day 10.5; Lrp2tm1Her/Lrp2tm1Her (more )
Structure Level Pattern Image Note
TS17: trunk mesenchyme derived from neural crest Present Regionally restricted 4L Neural crest cells in the left (pulmonary) side already reached the neural crest cells in the endocardial outflow tract.
Specimen 5G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Strong Regionally restricted 5G Expressed in the neurl crest cells around the pharyngeal arch arteries, and extending with prongs into the endocardial cushions.
Specimen 5J: embryonic day 11.5; Lrp2tm1Her/Lrp2tm1Her (more )
Structure Level Pattern Image Note
TS19: trunk mesenchyme derived from neural crest Present Regionally restricted 5J Expressed in neural crest cells on the left (pulmonary) side that connected to the neural crest cells in the endocardial cushions, which did not lead to septation of the aortic sac.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory